Olsalazine in patients intolerant of sulphasalazine.

Author: IrelandA, JewellD P

Paper Details 
Original Abstract of the Article :
Fifty patients with ulcerative colitis, intolerant of sulphasalazine, were treated with 500 mg olsalazine twice daily for a 3-month trial period. Thirty-eight of the patients (76%) tolerated the drug well, and all continued to take it beyond the 3-month period. Twelve (24%) were withdrawn because of...See full text at original site
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引用元:
https://doi.org/10.3109/00365528708991953

データ提供:米国国立医学図書館(NLM)

Olsalazine: An Alternative for Sulphasalazine-Intolerant Patients

Ulcerative colitis, a chronic inflammatory bowel disease, often requires medications like sulphasalazine to manage symptoms. However, some patients experience intolerance to sulphasalazine, making it challenging to find effective treatment options. This study, focusing on the field of gastroenterology, investigates the efficacy and tolerability of olsalazine in patients intolerant to sulphasalazine.

Olsalazine's Effectiveness in Sulphasalazine-Intolerant Patients

The study, conducted on patients with ulcerative colitis who were intolerant to sulphasalazine, found that olsalazine was well-tolerated by a significant proportion of patients. While some patients experienced side effects, such as diarrhea, olsalazine offered a viable alternative treatment option for those unable to tolerate sulphasalazine. This research underscores the importance of having alternative treatment options for patients with ulcerative colitis, especially those who experience intolerance to commonly used medications.

The Importance of Tailored Treatment for IBD

This study highlights the importance of personalized treatment approaches for patients with inflammatory bowel disease (IBD). It demonstrates that olsalazine can be a valuable alternative for patients who are intolerant to sulphasalazine. This research encourages further research to evaluate the long-term effectiveness and safety of olsalazine in managing ulcerative colitis.

Dr.Camel's Conclusion

Imagine a camel traversing a vast desert, encountering a patch of fertile ground. This research suggests that olsalazine, like this oasis, can provide a much-needed respite for patients with ulcerative colitis who are intolerant to sulphasalazine. It underscores the importance of finding tailored treatments that meet the unique needs of each individual with IBD.

Date :
  1. Date Completed 1988-02-04
  2. Date Revised 2019-08-14
Further Info :

Pubmed ID

2892247

DOI: Digital Object Identifier

10.3109/00365528708991953

Related Literature

SNS
PICO Info
in preparation
Languages

English

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