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The paw test: a behavioural paradigm for differentiating between classical and atypical neuroleptic drugs.
Author: CoolsA R, EllenbroekB A, HonigW M, PeetersB W
Original Abstract of the Article :
An often used animal model based on the effects of neuroleptics on spontaneous behaviour is the catalepsy test. However, this test seems to be particularly insensitive to the atypical neuroleptics thioridazine and, especially, clozapine. We have therefore developed an alternative test, the paw test,...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元：
https://doi.org/10.1007/BF00187254
データ提供：米国国立医学図書館（NLM）
The Paw Test: A New Compass for Navigating the Desert of Neuroleptics
The world of [neuroleptics] is a complex desert, filled with diverse drugs that can impact brain function and behavior. This study explores the potential of a new animal model, the [paw test], to differentiate between [classical neuroleptics] and [atypical neuroleptics]. It’s like finding a new compass to guide us through the desert of [neuroleptics], helping us understand the distinct effects of these drugs. The study compared the effects of various [neuroleptics] on the [paw test] and the [catalepsy test], seeking to identify potential differences in their effects on animal behavior. The authors meticulously analyzed the results, seeking to understand how different types of [neuroleptics] might affect the nervous system.
The Paw Test: A More Accurate Guide Through the Desert
The study found that the [paw test] was more effective in differentiating between [classical neuroleptics] and [atypical neuroleptics] than the [catalepsy test]. It’s like finding a more precise compass that helps us better navigate the complex terrain of [neuroleptics]. The researchers discovered that the [paw test] could accurately predict the profile of different [neuroleptics], potentially providing a valuable tool for understanding their effects and guiding their development.
Understanding Neuroleptics: A Journey Through the Desert
This study highlights the importance of developing new and more accurate tools for assessing the effects of [neuroleptics]. It’s like constantly refining our compasses and maps as we venture deeper into the desert of [neuroleptics], seeking a better understanding of these drugs and their potential benefits and risks. Further research is needed to explore the full potential of the [paw test] and its implications for understanding and developing more effective and safe neuroleptic drugs.
Dr.Camel's Conclusion
This study introduces the paw test as a promising new tool for distinguishing between classical and atypical neuroleptics. It provides a valuable new compass for navigating the complex terrain of neuroleptics, potentially leading to a better understanding of their effects and a more informed development of these drugs.
Date :
- Date Completed 1988-03-03
- Date Revised 2019-07-26
Further Info :
Related Literature
English
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