Comparison of the antihypertensive effects of betaxolol to atenolol.

Author: BarkerA H, BurrisJ F, CitronD C, HoganL B, McDonaldR H, MroczekW J

Paper Details 
Original Abstract of the Article :
A randomized double-blind multicenter study compared a new oral beta 1-adrenergic antagonist, betaxolol 10 to 40 mg (n = 71), with atenolol 25 to 100 mg (n = 75). Each drug was administered once daily for 24 weeks in patients with mild to moderate hypertension. Blood pressure (BP) measurements were ...See full text at original site
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引用元:
https://doi.org/10.1016/0002-9149(88)91071-5

データ提供:米国国立医学図書館(NLM)

Betaxolol vs. Atenolol: A Race Across the Desert

High blood pressure, like a relentless desert wind, can be a formidable foe. This study compared the antihypertensive effects of two beta-blockers, betaxolol and atenolol, in patients with mild to moderate hypertension. Imagine two camels, each carrying a different set of tools, traversing a desert landscape to combat the relentless wind.

Both drugs were shown to effectively reduce blood pressure, but betaxolol demonstrated a significantly greater reduction in diastolic blood pressure during the initial weeks of treatment. This is like one camel, equipped with a more effective set of tools, gaining a slight lead in the race against the wind.

A Close Race

Although betaxolol showed an initial advantage, the difference in blood pressure reduction between the two drugs diminished over time. It's like the two camels, despite their differing tools, eventually reaching a similar pace as they continue their journey across the desert.

Finding the Right Camel for Your Journey

The study suggests that betaxolol may be a more effective option for patients with mild to moderate hypertension, at least in the early stages of treatment. This is like choosing the camel with the most appropriate tools for navigating a particular desert landscape.

Dr. Camel's Conclusion

This study highlights the importance of carefully considering the specific needs of each patient when choosing an antihypertensive medication. It's like selecting the right camel for your desert adventure, taking into account the terrain, the wind, and the specific challenges you face along the way. The research underscores the dynamic nature of managing hypertension, emphasizing the need for ongoing monitoring and adaptation to ensure optimal outcomes.

Date :
  1. Date Completed 1988-04-22
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

2895577

DOI: Digital Object Identifier

10.1016/0002-9149(88)91071-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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