Treatment of ulcerative colitis with olsalazine and sulphasalazine: efficacy and side-effects.

Author: EckardtV, EweK, KanzlerG

Paper Details 
Original Abstract of the Article :
The effects of olsalazine were studied mainly in patients with ulcerative colitis who were intolerant to sulphasalazine, and for relapse prevention. A crossover design with sulphasalazine, 3 g/day, and olsalazine, 1.5 g/day, was applied to compare the side-effects of each drug and to evaluate their ...See full text at original site
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引用元:
https://doi.org/10.3109/00365528809101553

データ提供:米国国立医学図書館(NLM)

Olsalazine vs. Sulfasalazine for Ulcerative Colitis: Comparing Efficacy and Side Effects

Ulcerative colitis, a chronic inflammatory bowel disease, can significantly impact a patient's quality of life. This study investigates the efficacy and safety of olsalazine, a drug commonly used to treat ulcerative colitis, by comparing it to the well-established sulfasalazine. Researchers conducted a crossover study to assess the therapeutic effects of both drugs, paying particular attention to potential side effects.

Similar Efficacy, Reduced Side Effects: The Advantages of Olsalazine

The study's findings demonstrate that olsalazine is comparable to sulfasalazine in its therapeutic efficacy for treating mild or moderately severe ulcerative colitis. However, olsalazine stands out with a significantly lower incidence of side effects, making it a potentially more tolerable option for patients.

Navigating the Choices for Ulcerative Colitis Treatment

This study provides valuable information for clinicians and patients seeking effective treatment options for ulcerative colitis. The study's findings highlight the benefits of olsalazine, offering a potentially safer and equally effective alternative to sulfasalazine. It underscores the importance of considering individual patient needs and preferences when choosing the most appropriate treatment.

Dr.Camel's Conclusion

This study highlights the value of olsalazine as a safe and effective treatment option for ulcerative colitis. The study's findings demonstrate that olsalazine is comparable in efficacy to sulfasalazine, while offering the added benefit of reduced side effects. This research contributes to the ongoing efforts to improve the lives of those living with ulcerative colitis by providing a potentially more tolerable treatment option.

Date :
  1. Date Completed 1989-04-04
  2. Date Revised 2019-09-19
Further Info :

Pubmed ID

2906479

DOI: Digital Object Identifier

10.3109/00365528809101553

Related Literature

SNS
PICO Info
in preparation
Languages

English

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