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Phytotherapeutics: The Emerging Role of Intestinal and Hepatocellular Transporters in Drug Interactions with Botanical Supplements.

Author: , MukhtarFarah, MuneerSaiqa, MurtazaGhulam, NawazishShamyla, UllahNaveed

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Botanical supplements, often perceived as safe, can interact with drug transport and metabolism, potentially affecting drug efficacy and safety. This paper explores the interaction of botanical supplement ingredients with drug transporters like P-gp and OATPs, highlighting the clinical significance of these interactions.
Paper Details　
Original Abstract of the Article :
In herbalism, botanical supplements are commonly believed to be safe remedies, however, botanical supplements and dietary ingredients interact with transport and metabolic processes, affecting drug disposition. Although a large number of studies have described that botanical supplements interfere wi...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151444/

データ提供：米国国立医学図書館（NLM）

The Shifting Sands of Interactions: Exploring the Role of Transporters in Botanical Supplement and Drug Interactions

The field of [pharmacology] is a vast and ever-changing desert, where [understanding drug interactions] is crucial for [patient safety and efficacy]. This study explores the [emerging role of intestinal and hepatocellular transporters] in [interactions between botanical supplements and drugs]. The researchers emphasize the [importance of considering] these [transporter interactions] in [drug development and patient care], highlighting the potential for [serious undesired effects] from [botanical supplements].

A Desert Oasis of Knowledge: Unveiling the Potential Interactions Between Botanical Supplements and Drug Transporters

The study reveals the [complex interplay] between [botanical supplements, drug transporters, and drug disposition]. This knowledge could be critical for [optimizing drug efficacy] and [minimizing potential side effects] in patients who use [botanical supplements] alongside [prescription medications].

Navigating the Desert of Drug Interactions: Understanding the Importance of Transporter Interactions

This study emphasizes the [importance of consulting with healthcare professionals] before using [botanical supplements] alongside [medications]. It underscores the [need for careful consideration] of [potential interactions] and the [value of informed decision-making] to ensure [optimal health outcomes].

Dr.Camel's Conclusion

The desert of drug interactions can be treacherous, with hidden oases of knowledge waiting to be discovered. This study highlights the important role of transporters in interactions between botanical supplements and drugs, urging us to be vigilant in our understanding of these complex relationships to ensure safe and effective medication use.

Date :
  1. Date Completed 2018-06-11
  2. Date Revised 2018-12-07
Further Info :

Pubmed ID

29065448

DOI: Digital Object Identifier

PMC6151444

Related Literature

Article Analysis
・Effective treatment of herbalism
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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