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The Effects of <i>Morus alba</i> and <i>Acacia catechu</i> on Quality of Life and Overall Function in Adults with Osteoarthritis of the Knee.

Author: HewlingsSusan J, KalmanDouglas S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the effects of UP1306, a proprietary extract of Morus alba and Acacia catechu, on discomfort and function in adults with knee osteoarthritis. UP1306 was compared to glucosamine chondroitin and placebo. While all treatments showed improvements in discomfort and function, UP1306 was associated with a significant decrease in urinary C-telopeptides of type II collagen (CTX-II), a marker of cartilage degradation. This suggests that UP1306 may help to prevent joint cartilage damage in early stages of osteoarthritis.
Paper Details　
Original Abstract of the Article :
The purpose of this study was to determine the effects of UP1306 on discomfort and function in adults with osteoarthritis of the knee. In a randomized, double-blinded, placebo-controlled, parallel design, 135 subjects received UP1306, a standardized, proprietary extract of <i>Morus alba</i> and <i>A...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612321/

データ提供：米国国立医学図書館（NLM）

Morus alba and Acacia catechu for Osteoarthritis of the Knee

This study investigates the effects of a standardized extract of Morus alba and Acacia catechu (UP1306) on discomfort and function in adults with osteoarthritis of the knee. The study compared the effects of UP1306 to those of glucosamine chondroitin and placebo, using the WOMAC questionnaire and VAS (pain/discomfort) to assess outcomes.

UP1306: A Potential Therapeutic Agent for Osteoarthritis

The study found that UP1306 showed significant improvements in discomfort, stiffness, activities of daily living, range of motion, and distance walked compared to placebo. The research also observed a significant difference in urinary C-telopeptides of type II collagen (CTX-II), a marker of cartilage degradation, between UP1306 and placebo. These findings suggest that UP1306 may be a promising therapeutic agent for managing osteoarthritis.

Navigating the Desert of Joint Pain

Think of osteoarthritis as a challenging desert landscape, where joint pain and stiffness can make even simple tasks feel like a struggle. This study explores the potential benefits of a natural extract, UP1306, in alleviating these symptoms. The research highlights the importance of exploring alternative treatments for osteoarthritis, offering hope for a more comfortable and active life for those living with this condition.

Dr. Camel's Conclusion

This study explores the potential benefits of a natural extract, UP1306, in managing osteoarthritis of the knee. It's like a camel caravan discovering a refreshing oasis, providing relief from the pain and stiffness associated with this condition. The research highlights the importance of exploring natural remedies and alternative therapies for managing osteoarthritis, offering hope for a more comfortable and fulfilling life. As researchers, we must continue to delve into the vast and complex world of natural compounds, uncovering new and effective solutions for treating a wide range of ailments.
Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

29085676

DOI: Digital Object Identifier

PMC5612321

SNS
PICO Info
in preparation
Languages

English

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