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Drooling Reduction Intervention randomised trial (DRI): comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability.

Author: CadwganJill, ColeMike, ColverAllan F, O'HareAnne E, ParrJeremy R, PenningtonLindsay, StockenDeborah, TodhunterEmma, TuffreyCatherine, WilliamsJane

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Pragmatic Clinical TrialA trial conducted in a real-world clinical setting. It evaluates the effectiveness of interventions in everyday healthcare environments.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Hyoscine patches and glycopyrronium liquid are effective treatments for drooling in children with neurodisability. While both treatments reduced drooling, hyoscine led to more side effects and a higher chance of treatment cessation. 55% of children on hyoscine continued treatment at week 12 compared to 82% on glycopyrronium.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Investigate whether hyoscine patch or glycopyrronium liquid is more effective and acceptable to treat drooling in children with neurodisability. DESIGN: Multicentre, single-blind, randomised controlled trial. SETTING: Recruitment through neurodisability teams; treatment by parents. PAR...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890631/

データ提供：米国国立医学図書館（NLM）

Drooling Relief: A Comparative Study of Hyoscine Patches and Glycopyrronium Liquid

The desert of [Neurodisability] can be a challenging landscape for children, often leading to difficulties with [Drooling]. This study, like a camel seeking out a refreshing oasis, compares the effectiveness and acceptability of two medications, [Hyoscine patches] and [Glycopyrronium liquid], in treating drooling in children with neurodisability. Researchers conducted a [multicenter, single-blind, randomized controlled trial] to evaluate the impact of these treatments on drooling severity and patient satisfaction. The findings highlight the potential benefits of both medications, providing valuable insights into the management of drooling in this population.

A Comparative Oasis: Finding Relief from Drooling

This study provides valuable information for parents and healthcare professionals caring for children with neurodisability. The research suggests that both hyoscine patches and glycopyrronium liquid can effectively reduce drooling, offering a range of treatment options to address this challenging condition. The study highlights the importance of considering individual patient preferences and tolerance when selecting the most appropriate treatment approach.

A Sip of Comfort: Improving Quality of Life for Children with Neurodisability

This research offers hope for families dealing with the challenges of drooling in children with neurodisability. The study highlights the effectiveness of both hyoscine patches and glycopyrronium liquid in reducing drooling, potentially improving quality of life for both children and their families. The findings underscore the importance of continued research into effective and safe treatments for this condition, enabling children to live fuller and more comfortable lives.

Dr. Camel's Conclusion

This study is a reminder that the desert of neurodisability can be a challenging landscape for children and their families. However, with the help of innovative treatments and compassionate care, we can provide children with the support they need to navigate this terrain with greater ease. This research is a testament to the commitment of healthcare professionals to improving the lives of children with neurodisability.

Date :
  1. Date Completed 2019-01-25
  2. Date Revised 2019-01-25
Further Info :

Pubmed ID

29192000

DOI: Digital Object Identifier

PMC5890631

Related Literature

Article Analysis
・Side Effects of glycopyrrolate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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