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Oligosaccharide nanomedicine of alginate sodium improves therapeutic results of posterior lumbar interbody fusion with cages for degenerative lumbar disease in osteoporosis patients by downregulating serum miR-155.
Author: DongRongpeng, KangMingyang, QuYang, WangZhengming, ZhaoJianwu, ZhouHaohan
Original Abstract of the Article :
Degenerative lumbar disease (DLD) is a significant issue for public health. Posterior lumbar intervertebral fusion with cages (PLIFC) has high-level fusion rate and realignment on DLD. However, there are some complications following the surgery. Alginate oligosaccharides (AOS) have antioxidant and a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703176/
データ提供:米国国立医学図書館(NLM)
Oligosaccharide Nanomedicine: A New Approach to Posterior Lumbar Interbody Fusion
This research explores the use of oligosaccharide nanomedicine of alginate sodium (ONAS) in enhancing the therapeutic outcomes of posterior lumbar interbody fusion (PLIFC) for degenerative lumbar disease in osteoporosis patients. It's like discovering a hidden oasis in the desert of orthopedic surgery, seeking innovative solutions to improve bone healing and reduce complications. The authors meticulously investigate the effects of ONAS on serum miR-155 levels, inflammation, and bone fusion, comparing its efficacy to conventional treatment. The study's findings provide compelling evidence that ONAS offers a promising new approach to PLIFC, promoting bone healing and reducing infection risk.
ONAS: A Novel Therapeutic Approach for PLIFC
The study's findings demonstrate the efficacy of ONAS in improving therapeutic outcomes of PLIFC in osteoporosis patients. It's like finding a new irrigation system for the desert, delivering essential nutrients and promoting the growth of a healthy ecosystem. ONAS effectively downregulates serum miR-155 levels, reducing inflammation and promoting bone fusion. These results suggest that ONAS could be a valuable tool for improving the success rates of PLIFC, leading to better outcomes and faster recovery for patients.
Promoting Bone Healing and Reducing Complications
Imagine a desert oasis where a complex network of canals irrigates the land, nourishing plants and promoting their growth. ONAS acts similarly in the body, delivering vital nutrients to the bone and promoting its healing. By regulating serum miR-155 levels and reducing inflammation, ONAS helps create a conducive environment for bone fusion, leading to faster recovery and a lower risk of complications. It's a testament to the power of nanotechnology and its potential to revolutionize bone regeneration and repair.
Dr. Camel's Conclusion
This study is a reminder that even in the arid landscape of orthopedic surgery, there is always room for innovation and progress. ONAS offers a promising new approach to PLIFC, potentially leading to faster recovery, reduced complications, and improved outcomes for patients with degenerative lumbar disease. It's a testament to the ongoing quest for better and more effective treatments, offering a beacon of hope for a future where bone healing is optimized and patients experience faster recovery times.
Date :
- Date Completed 2018-03-09
- Date Revised 2018-12-02
Further Info :
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