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Abstinence following toluene exposure increases anxiety-like behavior in mice.
Author: BowenScott E, CallanSean P, DavidsonCameron J, HanniganJohn H
Original Abstract of the Article :
The intentional misuse of volatile solvents like toluene is a persistent public health concern. Limited clinical data suggest that chronic inhalant abusers may experience signs of withdrawal, including anxiety. Behavioral withdrawal from toluene has not been examined in a preclinical model. In the c...See full text at original site
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引用元：
https://doi.org/10.1016/j.ntt.2017.12.010
データ提供：米国国立医学図書館（NLM）
Toluene Abuse: A Look at the Unseen Effects
This study delves into the [effects of toluene exposure] on [anxiety-like behavior] in mice. The authors used [behavioral testing] to examine the impact of [acute and prolonged toluene exposure] on [anxiety levels] in mice. This research is important because it sheds light on the [potential behavioral consequences] of [toluene abuse] and contributes to our understanding of [inhalant withdrawal syndrome].
The study found that [acute toluene exposure] led to a [decrease in anxiety-like behavior], whereas [abstinence from prolonged toluene exposure] resulted in an [increase in anxiety-like behavior]. These findings suggest that [toluene withdrawal] may trigger [anxiety symptoms] in mice. The researchers also observed that [re-exposure to toluene] could [ameliorate the anxiety-like behavior] observed during [abstinence].
The Hidden Cost of Toluene Abuse: Anxiety in Withdrawal
This study reveals the potential for [toluene abuse] to trigger [anxiety symptoms] during [withdrawal]. It’s like a mirage in the desert - a deceptive appearance of calm that quickly gives way to distress. The findings highlight the importance of [addressing anxiety] in [individuals with toluene use disorder] and [providing support] during [withdrawal].
Understanding and Managing Toluene Withdrawal
This research underscores the need for [comprehensive care] for [individuals with toluene use disorder]. It’s like navigating a treacherous desert - awareness of the risks and challenges is essential for safety and well-being. Treatment should address both the [physical and psychological] aspects of [toluene withdrawal] to [reduce the risk of relapse] and [improve overall health outcomes].
Dr.Camel's Conclusion
This study demonstrates the potential for toluene abuse to trigger anxiety symptoms during withdrawal. The findings highlight the importance of addressing anxiety in individuals with toluene use disorder and providing support during withdrawal. This research underscores the need for comprehensive care for individuals with toluene use disorder, addressing both the physical and psychological aspects of withdrawal to reduce the risk of relapse and improve overall health outcomes. It’s like navigating a treacherous desert - awareness of the risks and challenges is essential for safety and well-being.
Date :
- Date Completed 2019-10-31
- Date Revised 2019-10-31
Further Info :
Related Literature
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