In vitro efficacy of tavaborole topical solution, 5% after penetration through nail polish on ex vivo human fingernails.

Author: BrownMarc, FoleyKelly A, GuptaAditya K, HallSteve, LoweNicole Gellings, TurnerRob, VlahovicTracey C

Paper Details 
Original Abstract of the Article :
BACKGROUND: Topical antifungal treatments for onychomycosis are applied to clean, unpolished nails for 48 weeks or longer. Patients often wish to mask their infection with nail polish yet there is no evidence to suggest antifungal efficacy in the presence of nail polish. OBJECTIVE: To determine if ...See full text at original site
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引用元:
https://doi.org/10.1080/09546634.2017.1422078

データ提供:米国国立医学図書館(NLM)

Tavaborole: A Potential Solution for Onychomycosis, Even Under Nail Polish

The study of fungal infections, particularly those affecting the nails (onychomycosis), is a critical area of research, with researchers seeking effective and convenient treatment options. This paper investigates the efficacy of tavaborole, a topical antifungal medication, in treating onychomycosis, even when applied under nail polish. The research offers promising evidence for the potential of tavaborole to overcome a common obstacle in treating nail fungal infections.

Tavaborole: A Trailblazer in Nail Fungus Treatment

The study found that tavaborole retained its antifungal activity even when applied under nail polish. This finding is significant because it suggests that patients can potentially mask their infection with nail polish while still receiving effective treatment with tavaborole. Think of it like a camel caravan navigating a desert landscape, with the caravan leader able to effectively guide the group even when obscured by a sandstorm.

Navigating the Desert of Nail Fungus Treatment with Tavaborole

The study highlights the potential for tavaborole to improve patient compliance with treatment. The ability to apply tavaborole under nail polish may encourage patients to continue treatment, even while maintaining a more aesthetically pleasing appearance. This is like a desert traveler discovering a shortcut through a treacherous landscape, making the journey more manageable and achievable.

Dr.Camel's Conclusion

This study offers a ray of hope for individuals struggling with nail fungus. Tavaborole's ability to effectively penetrate the nail plate even when applied under nail polish could potentially revolutionize the treatment of onychomycosis, making treatment more convenient and patient-friendly.

Date :
  1. Date Completed 2018-09-04
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

29307243

DOI: Digital Object Identifier

10.1080/09546634.2017.1422078

Related Literature

SNS
PICO Info
in preparation
Languages

English

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