Paper Details 
Original Abstract of the Article :
BACKGROUND: Deflazacort (DFZ), an oxazoline derivative of prednisolone (PDN), has a dose equivalence of 1.2:1 (mg) to PDN. No study to date has compared adverse effects and efficacy of high doses of DFZ as against high-dose PDN in systemic lupus erythematosus (SLE). OBJECTIVES: To compare adverse e...See full text at original site
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引用元:
https://doi.org/10.1177/0961203317751854

データ提供:米国国立医学図書館(NLM)

Deflazacort vs. Prednisolone: A Desert Oasis of Treatment Options

The treatment of [systemic lupus erythematosus (SLE)] often involves [corticosteroids], but finding the right type and dose can be a challenging journey. This study compares the adverse effects and efficacy of [deflazacort] and [prednisolone], two commonly used corticosteroids, in patients with SLE. It's like exploring different routes across a vast desert, seeking the most effective and least burdensome path to manage the condition.

Deflazacort: A Potential Advantage in Managing SLE

The study found that high doses of deflazacort were associated with lower weight gain, hirsutism, and cushingoid features compared to prednisolone, while maintaining similar efficacy. This is like finding a desert oasis with less sand and more water: providing relief from the adverse effects of traditional corticosteroids.

Potential for Personalized Treatment

The study suggests that deflazacort may be a viable alternative to prednisolone in the treatment of SLE, potentially offering a less burdensome option with similar efficacy. It's like discovering a new route across the desert: providing a more comfortable and efficient journey to manage the condition.

Dr.Camel's Conclusion

This research offers a new oasis in the desert of SLE treatment, highlighting the potential benefits of deflazacort over prednisolone. It's a step towards finding more personalized and effective treatment options for this complex and challenging condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-05-25
Further Info :

Pubmed ID

29320974

DOI: Digital Object Identifier

10.1177/0961203317751854

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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