New Therapeutic Approaches for the Treatment of Hyperkalemia in Patients Treated with Renin-Angiotensin-Aldosterone System Inhibitors.

Author: CaballeroRicardo, DelpónEva, TamargoJuan

Paper Details 
Original Abstract of the Article :
Hyperkalemia (serum potassium &gt;&#8201;5.5&#160;mEq/L) is a common clinical problem in patients with chronic kidney disease, hypertension, diabetes, and heart failure. It can result from increased K<sup>+</sup> intake, impaired distribution between intracellular and extracellular spaces, and most ...See full text at original site
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引用元:
https://doi.org/10.1007/s10557-017-6767-5

データ提供:米国国立医学図書館(NLM)

Hyperkalemia: Navigating the Desert of Electrolyte Imbalance

Maintaining electrolyte balance is crucial for proper body function, and disruptions in potassium levels can lead to serious health consequences. This review examines the challenges of hyperkalemia, an excess of potassium in the blood, particularly in patients treated with renin-angiotensin-aldosterone system inhibitors (RAASIs), medications commonly used to manage cardiovascular conditions. The authors delve into the underlying mechanisms of hyperkalemia, its prevalence, and the limitations of existing treatment options, highlighting the need for novel approaches to control potassium levels while maintaining RAAI therapy.

New Therapeutic Approaches for Hyperkalemia

The review presents two new polymer-based agents, patiromer calcium and sodium zirconium cyclosilicate, designed to bind potassium in the gastrointestinal tract, increasing fecal potassium loss and normalizing serum potassium levels. These agents offer promising solutions for managing hyperkalemia in patients receiving RAAI therapy, providing a potential oasis in the desert of electrolyte imbalance.

Navigating the Desert of Hyperkalemia Management

This review provides valuable insights for healthcare providers managing hyperkalemia, highlighting the complexities of potassium homeostasis and the limitations of traditional treatments. The introduction of new polymer-based agents offers hope for more effective and safe management of hyperkalemia in patients who rely on RAAI therapy for cardiovascular health. As we continue to explore the desert of electrolyte balance, we seek to develop innovative approaches to ensure optimal potassium levels, supporting overall health and well-being.

Dr.Camel's Conclusion

This review, like a caravan navigating a treacherous desert landscape, explores the challenges of hyperkalemia, a common complication for patients receiving RAAI therapy. The emergence of new, non-systemic potassium binders offers a beacon of hope for managing this condition, providing a crucial tool for maintaining electrolyte balance and optimizing cardiovascular health. As we journey through the desert of medical research, we strive to develop more effective and personalized approaches to managing electrolyte imbalances, ensuring the well-being of patients facing these challenges.

Date :
  1. Date Completed 2019-01-29
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

29372448

DOI: Digital Object Identifier

10.1007/s10557-017-6767-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

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