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Effectiveness of Rotigotine plus intensive and goal-based rehabilitation versus Rotigotine alone in "de-novo" Parkinsonian subjects: a randomized controlled trial with 18-month follow-up.

Author: FerrazzoliD, FrazzittaG, MaestriR, OrtelliP, RiboldazziG

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Dopamine replacement therapy is the most effective treatment for Parkinson's disease (PD), but some symptoms don't improve and long-term use can cause side effects. Dopamine agonists are often used for people newly diagnosed with PD. Several studies have shown that rehabilitation can be helpful for PD.
Paper Details　
Original Abstract of the Article :
Dopamine Replacement Therapy (DRT) represents the most effective treatment for Parkinson's disease (PD). Nevertheless, several symptoms are unresponsive to treatment and its long-term use leads to serious side effects. To optimize the pharmacological management of PD, dopamine-agonists are often pre...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878188/

データ提供：米国国立医学図書館（NLM）

Rotigotine and Rehabilitation: A New Oasis in the Desert of Parkinson's Disease

This randomized controlled trial investigates the effectiveness of rotigotine, a dopamine agonist, in combination with intensive, goal-based rehabilitation for treating Parkinson's disease (PD). The authors compared the effects of rotigotine alone with rotigotine plus rehabilitation in newly diagnosed PD patients. Their findings revealed that rotigotine combined with rehabilitation led to significant improvements in motor function and quality of life compared to rotigotine alone. This study suggests that integrating rehabilitation into the treatment of PD can enhance therapeutic outcomes.

A Holistic Approach to Parkinson's Treatment

The study's findings emphasize the importance of a multi-disciplinary approach to managing PD, incorporating both medication and rehabilitation. Integrating rehabilitation into treatment plans can enhance motor function, improve quality of life, and potentially delay disease progression.

A Beacon of Hope in the Desert of Parkinson's Disease

This research offers a promising new strategy for treating PD, highlighting the benefits of combining medication with rehabilitation. The findings, like a refreshing oasis in the vast desert of PD, suggest that a holistic approach can significantly improve the lives of individuals living with this challenging condition.

Dr.Camel's Conclusion

This study demonstrates the potential of combining rotigotine, a dopamine agonist, with intensive, goal-based rehabilitation to improve outcomes for newly diagnosed Parkinson's disease patients. The findings suggest that this multi-disciplinary approach can enhance motor function, improve quality of life, and potentially delay disease progression. This research, like a caravan navigating the shifting sands of Parkinson's disease, underscores the importance of seeking innovative and comprehensive treatment strategies.

Date :
  1. Date Completed 2018-09-07
  2. Date Revised 2020-03-06
Further Info :

Pubmed ID

29442177

DOI: Digital Object Identifier

PMC5878188

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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