Pyridoxine Add-On Treatment for the Control of Behavioral Adverse Effects Induced by Levetiracetam in Children: A Case-Control Prospective Study.

Author: FalsaperlaRaffaele, MarinoSilvia, MarinoSimona Domenica, PavonePiero, ProvvidentiSimona, RomanoCatia, VitalitiGiovanna

Paper Details 
Original Abstract of the Article :
BACKGROUND: Few studies on adult and pediatric patients have shown pyridoxine efficacy as additional therapy for those receiving levetiracetam (LEV) to prevent and mitigate behavioral adverse effects (BAEs). OBJECTIVE: The aim of our study was to analyze the safety and efficacy of pyridoxine supple...See full text at original site
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引用元:
https://doi.org/10.1177/1060028018759637

データ提供:米国国立医学図書館(NLM)

Pyridoxine: A Potential Solution for Levetiracetam-Induced Behavioral Issues in Children

The world of pediatric neurology is a vast and complex desert, where the delicate balance of brain development and medication management is a constant challenge. This study, like a research expedition exploring a new oasis, investigates the use of pyridoxine, a form of vitamin B6, as an add-on therapy to help manage behavioral adverse effects (BAEs) induced by levetiracetam (LEV), a common anti-epileptic medication in children. The researchers, like skilled desert navigators, employed a randomized, case-control trial to carefully assess the safety and efficacy of pyridoxine supplementation.

A Promising Solution

The study, like a shimmering oasis in the desert, revealed that pyridoxine supplementation may be a safe and effective way to manage LEV-induced BAEs in children. The study showed that patients who received pyridoxine after 1 month of LEV treatment did not need to change or stop LEV treatment and experienced an improvement in BAEs within approximately 9 days.

Navigating the Desert of Pediatric Neurology

Navigating the desert of pediatric neurology requires constant attention to detail and a commitment to finding solutions that improve the lives of children. This study provides a glimmer of hope in the management of LEV-induced BAEs, offering a potential solution that can improve quality of life for children and their families. The researchers, like explorers returning from a successful expedition, have provided valuable insights into the potential benefits of pyridoxine as an add-on therapy, paving the way for further exploration of its therapeutic potential.

Dr.Camel's Conclusion

This study, like a cool breeze in the desert, offers a refreshing perspective on the management of LEV-induced BAEs in children. The findings suggest that pyridoxine supplementation may be a safe and effective way to improve behavioral outcomes for these patients. As we continue to navigate the vast desert of pediatric neurology, research like this serves as a beacon of hope, illuminating new pathways to better care for our youngest patients.

Date :
  1. Date Completed 2019-09-18
  2. Date Revised 2019-09-18
Further Info :

Pubmed ID

29442544

DOI: Digital Object Identifier

10.1177/1060028018759637

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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