Emerging therapies for neuropathic pain: new molecules or new indications for old treatments?

Author: AttalNadine, BouhassiraDidier

Paper Details 
Original Abstract of the Article :
Neuropathic pain represents a highly unmet medical need because most of the available treatments have a modest efficacy or dose-limiting side effects. Hence, novel therapeutic perspectives are warranted. Many compounds acting on new pain targets are in preclinical or early clinical development. Only...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/29447137

データ提供:米国国立医学図書館(NLM)

Emerging Therapies for Neuropathic Pain: New Molecules or New Indications for Old Treatments?

Neuropathic pain, a complex and often debilitating condition, has long been a challenge for healthcare professionals. Imagine the relentless sting of a scorpion, but without the scorpion! This is the nature of neuropathic pain, a persistent, burning, or shooting sensation that arises from damage to the nervous system. This study explores the latest advancements in neuropathic pain treatment, exploring the use of both novel molecules and repurposing existing drugs for this painful condition. The researchers are like explorers traversing a vast desert landscape, seeking new paths to alleviate this persistent pain. They analyzed the potential of new pain targets and clinical trials of existing medications, with a focus on NaV1.7 antagonists and angiotensin type II inhibitors, as well as the innovative use of botulinum toxin A and the antiepileptic oxcarbazepine. The study also dives into the promising field of noninvasive brain neurostimulation techniques, such as repetitive transcranial magnetic stimulation and transcranial direct electrical stimulation, to explore new avenues for pain relief. This research provides a comprehensive overview of emerging therapies, offering a glimmer of hope for patients suffering from neuropathic pain.

A New Dawn for Neuropathic Pain Treatment

This research offers a ray of hope for patients struggling with neuropathic pain, highlighting the growing arsenal of treatments. It's like a gentle breeze blowing through the desert, bringing relief to those who have endured the pain for so long. The study suggests that the future of neuropathic pain treatment is promising, with several promising new therapies in development. This study provides a valuable roadmap for researchers, clinicians, and pharmaceutical companies to accelerate the development and implementation of effective treatments for neuropathic pain.

Implications for Pain Management

This study encourages the development of new pain management strategies, taking a multi-pronged approach to address the complex nature of neuropathic pain. It's like building a network of oasis in the desert, offering various points of respite and healing. This research highlights the need for further investigation into the efficacy and safety of emerging therapies, as well as the development of personalized treatment plans to meet the unique needs of each patient. This research is a reminder that the journey towards effective pain management is ongoing, with a constant need for exploration and innovation.

Dr. Camel's Conclusion

This research is a beacon of hope in the vast desert of chronic pain. The journey to find effective treatments for neuropathic pain continues, but with the emergence of new therapies and the dedication of researchers, we are closer than ever to a future where this debilitating condition can be effectively managed.

Date :
  1. Date Completed 2019-04-01
  2. Date Revised 2021-01-13
Further Info :

Pubmed ID

29447137

DOI: Digital Object Identifier

00006396-201803000-00021

Related Literature

SNS
PICO Info
in preparation
Languages

English

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