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Effects of adjunctive eslicarbazepine acetate on neurocognitive functioning in children with refractory focal-onset seizures.
Author: GamaH, JóźwiakSergiusz, MoreiraJ, RochaF, Soares-da-SilvaP, VeggiottiP
Original Abstract of the Article :
PURPOSE: This was a phase-II, randomized, double-blind (DB), placebo-controlled study aimed to evaluate neurocognitive effects of eslicarbazepine acetate (ESL) as adjunctive therapy in pediatric patients with refractory focal-onset seizures (FOS). METHODS: Children (6-16years old) with FOS were ran...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.yebeh.2018.01.029
データ提供:米国国立医学図書館(NLM)
Eslicarbazepine Acetate for Refractory Seizures: A Camel's Search for Cognitive Stability
Refractory focal-onset seizures are a challenging condition that can significantly impact a child's life. It's like a sandstorm in the desert, disrupting the flow of life and creating unpredictable challenges. This research investigates the neurocognitive effects of eslicarbazepine acetate (ESL) as an adjunctive therapy for children with refractory focal-onset seizures. It's a quest to find a medication that can both control seizures and minimize any potential impact on cognitive function. The researchers found that while ESL was effective in reducing seizure frequency and was well-tolerated, it did not have a significant positive impact on neurocognitive function. It's like finding a temporary oasis in the desert, offering relief from the storm but not completely restoring the original landscape.
Navigating Seizures and Cognitive Function: A Camel's Perspective
This research highlights the complexities of managing refractory focal-onset seizures in children. It's a reminder that finding the right balance between controlling seizures and minimizing cognitive side effects is a delicate dance. It's like a camel caravan navigating a desert, needing to carefully choose its route to avoid dangers while still reaching its destination.
A Camel's Guide to Epilepsy Management
This research provides valuable insights for parents and caregivers of children with refractory focal-onset seizures. While ESL can be an effective treatment option for seizure control, it's important to be aware of its potential impact on cognitive function and to monitor for any changes. It's a reminder that managing epilepsy requires a multi-faceted approach, including careful monitoring and ongoing communication with healthcare providers.
Dr. Camel's Conclusion
This research is a reminder that the search for effective and safe treatments for refractory focal-onset seizures is ongoing. While ESL offers a valuable tool for seizure control, it's important to consider its potential impact on cognitive function and to continue exploring other treatment options.
Date :
- Date Completed 2019-03-14
- Date Revised 2019-03-14
Further Info :
Related Literature
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