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Use of ipratropium bromide in asthma. Results of a multi-clinic study.

Author: BodmanS F, BushR K, BusseW W, FalliersC J, NathanR A, O'HollarenJ D, StormsW W, WegJ G

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.

Overview

Ipratropium bromide and metaproterenol were both effective bronchodilators for patients with asthma. The only significant side effects of ipratropium bromide were cough and exacerbation of symptoms.
Paper Details　
Original Abstract of the Article :
A multi-center, double-blind, 90-day study compared an ipratropium bromide metered-dose inhaler (40 microgram four times a day) with a metaproterenol metered-dose inhaler (1,500 micrograms four times a day) in 164 patients with asthma; of the 144 patients who completed the study, 71 received ipratro...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9343(86)90464-x

データ提供：米国国立医学図書館（NLM）

Ipratropium Bromide for Asthma: Exploring the Benefits

Asthma, a chronic respiratory condition, can significantly affect breathing and quality of life. Imagine a camel struggling to breathe in a desert sandstorm. That's what asthma can feel like for many individuals. This research investigates the effectiveness of ipratropium bromide, a medication used to open airways, in managing asthma.

The researchers conducted a multi-center study comparing ipratropium bromide to metaproterenol, another common bronchodilator. They found that both medications were effective in opening airways and improving lung function, but with different kinetic profiles. Ipratropium bromide had a slower onset of action but a longer duration of effect. It's like choosing a different type of camel for a desert journey, considering its strengths and weaknesses based on the specific terrain and the needs of the traveler.

Navigating the Options for Asthma Management

This study provides valuable insights into the effectiveness of ipratropium bromide for asthma, highlighting its potential as an effective treatment option. The researchers recommend careful consideration of the drug's kinetic profile when choosing the appropriate medication for individual patients. It's like understanding the different types of terrain in a desert and selecting the camel that is best suited for each segment of the journey.

Improving Asthma Control and Quality of Life

This research underscores the importance of finding the right treatment for asthma, ensuring effective management and improved quality of life for patients. It's like finding the optimal path through the desert, maximizing comfort and ensuring a successful journey. By understanding the different options and tailoring treatment plans to individual needs, healthcare providers can help patients navigate the challenges of asthma and live fulfilling lives.

Dr. Camel's Conclusion

This study offers valuable insights into the effectiveness of ipratropium bromide for asthma, emphasizing the importance of personalized treatment approaches. It's a reminder that in the vast desert of medicine, there are often multiple paths to success, and finding the right one for each patient is crucial.

Date :
  1. Date Completed 1986-12-23
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

2947462

DOI: Digital Object Identifier

10.1016/0002-9343(86)90464-x

Related Literature

Article Analysis
・Side Effects of metaproterenol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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