Paper Details 
Original Abstract of the Article :
Palmitoyl-glycine-histidine (Pal-GH) is a new low molecular weight gelling agent. It exhibits thixotropic behavior, low viscosity, and high dissolving properties for a wide range of hydrophilic to lipophilic drugs. Orally administered ivermectin (IVM) is used to treat scabies. However, this treatmen...See full text at original site
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引用元:
https://doi.org/10.1248/cpb.c17-00965

データ提供:米国国立医学図書館(NLM)

Scabies Treatment: A New Approach to Combating an Itchy Desert

Scabies, a skin infestation, can be a real itch in the desert of our lives. Ivermectin, a commonly used medication for scabies, is typically administered orally. However, this route can lead to side effects. This research explores a new approach, investigating the potential of a topically applied gel spray formulation containing ivermectin to treat scabies. The researchers formulated a gel spray using a novel gelling agent, palmitoyl-glycine-histidine (Pal-GH), and evaluated its effectiveness in delivering ivermectin to the skin of hairless rats.

A Oasis of Innovation: Topical Ivermectin Delivery

This study presents a novel approach to scabies treatment, potentially offering an alternative to oral administration with fewer side effects.

A Gentle Breeze Across the Desert: Treating Scabies Effectively

The research suggests that topical delivery of ivermectin using a Pal-GH gel spray formulation may offer a more effective and potentially safer approach to treating scabies.

Dr.Camel's Conclusion

Scabies can feel like an endless itch in the desert. This research explores a new way to combat this pesky condition, potentially offering a more comfortable and effective treatment option. The innovative use of a gel spray formulation may bring a new wave of relief to those struggling with this common condition.

Date :
  1. Date Completed 2018-03-27
  2. Date Revised 2018-03-27
Further Info :

Pubmed ID

29491265

DOI: Digital Object Identifier

10.1248/cpb.c17-00965

Related Literature

SNS
PICO Info
in preparation
Languages

English

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