Effects of sumatriptan nasal spray (Imigran) on human nasal mucosa.

Author: ChengL-H, ChuY-H, LinY-Y, WangH-W, WuP-C

Paper Details 
Original Abstract of the Article :
Label="OBJECTIVES" NlmCategory="OBJECTIVE">Sumatriptan (Imigran) is a potent and highly selective 5-HT<sub>1</sub> receptor agonist often used in treating acute migraine. Intranasal sumatriptan is well absorbed and is generally effective in relieving headache. However, the effects of Imigran on huma...See full text at original site
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引用元:
https://doi.org/10.1111/coa.13091

データ提供:米国国立医学図書館(NLM)

Exploring the Nasal Impact of Sumatriptan: A Journey Through the Mucosa

Sumatriptan, a well-known migraine treatment, is often administered as a nasal spray. While its effectiveness in relieving headache is widely recognized, the effects of sumatriptan on the human nasal mucosa itself have been largely unexplored. This research aims to fill this knowledge gap by investigating the direct effects of Imigran (sumatriptan nasal spray) on human nasal mucosa in vitro. This study sheds light on the direct impact of sumatriptan on the nasal mucosa, a crucial aspect in understanding the drug's overall safety and efficacy.

Understanding the Local Impact of Sumatriptan

This study is a valuable step in understanding the local effects of sumatriptan on the nasal mucosa. The findings could provide valuable insights for optimizing drug delivery and minimizing potential side effects. Further research is needed to evaluate the long-term impact of sumatriptan on nasal mucosa in a clinical setting.

Knowing Your Nose: A Journey Through the Mucosa

This research reminds us that even seemingly localized treatments, like nasal sprays, can have effects beyond their intended target. It's essential to consider the potential impact of medications on the tissues they come into contact with. Further research is needed to fully understand the safety and efficacy of sumatriptan nasal spray in the long term, and to explore alternative delivery methods that might minimize potential side effects.

Dr.Camel's Conclusion

This research takes us on a journey through the nasal mucosa, revealing the direct effects of sumatriptan on this delicate tissue. The findings highlight the importance of considering the local effects of medications beyond their intended target. This research is a step towards a more comprehensive understanding of sumatriptan's impact and could lead to improvements in drug delivery and safety.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-07-27
Further Info :

Pubmed ID

29495103

DOI: Digital Object Identifier

10.1111/coa.13091

Related Literature

SNS
PICO Info
in preparation
Languages

English

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