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Efficacy and safety of topical tranexamic acid in knee arthroplasty.

Author: Dauder-GallegoCristina, Ferreño-MárquezDavid, López-HualdaÁlvaro, Martínez-MartínJavier

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

This study aimed to evaluate the efficacy and safety of topical tranexamic acid (TXA) in total knee arthroplasty.
Paper Details　
Original Abstract of the Article :
Tranexamic acid (TXA) is commonly used to control postoperative blood loss in total knee arthroplasty. In order to avoid adverse effects associated with intravenous administration, topical use has been proposed as an alternative. Our aim was to evaluate the efficacy and safety of topical TXA in tota...See full text at original site
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引用元：
https://doi.org/10.1016/j.medcli.2018.01.017

データ提供：米国国立医学図書館（NLM）

Topical Tranexamic Acid: A Safer Approach for Controlling Blood Loss in Knee Arthroplasty

Total knee arthroplasty is a common surgical procedure, but it can lead to significant postoperative blood loss. Tranexamic acid (TXA) is often used to control this bleeding, but intravenous administration can lead to adverse effects. This study investigates the efficacy and safety of topical TXA as an alternative route of administration for controlling blood loss in knee arthroplasty.

Topical Tranexamic Acid: A Promising Alternative for Controlling Blood Loss in Knee Arthroplasty

The study found that topical TXA is an effective and safe alternative to intravenous administration in controlling blood loss after knee arthroplasty. By applying TXA directly to the surgical site, the researchers aimed to minimize systemic exposure and potentially reduce side effects. These findings offer valuable insights for orthopedic surgeons seeking to improve patient outcomes while minimizing the risk of complications.

Optimizing Knee Arthroplasty Outcomes: A Focus on Safety and Effectiveness

The study highlights the importance of finding safe and effective strategies for managing postoperative blood loss in knee arthroplasty. Topical TXA emerges as a promising alternative to intravenous administration, potentially reducing the risk of adverse effects. This study encourages ongoing research to further refine the use of topical TXA and optimize patient outcomes after knee arthroplasty.

Dr. Camel's Conclusion

This study offers a glimpse into the evolving landscape of surgical procedures, with a focus on improving safety and effectiveness. Just as a camel adapts to the desert environment, surgeons must constantly innovate to find better ways to care for their patients. This study highlights the potential of topical TXA in minimizing blood loss and optimizing outcomes for knee arthroplasty patients.

Date :
  1. Date Completed 2019-10-28
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

29496242

DOI: Digital Object Identifier

10.1016/j.medcli.2018.01.017

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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