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Histopathologic evaluation of the effects of etodolac in established adjuvant arthritis in rats: evidence for reversal of joint damage.
Author: ChauT T, RonaG, WeichmanB M
Original Abstract of the Article :
Histopathologic evaluation of hindpaws from control rats with established adjuvant arthritis showed severe alterations in soft tissue and bone, as well as progressive, moderate-to-severe articular changes. Following treatment with etodolac for 28 days, soft tissue and articular changes were rated mi...See full text at original site
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引用元:
https://doi.org/10.1002/art.1780300419
データ提供:米国国立医学図書館(NLM)
Etodolac and Adjuvant Arthritis: A Desert Oasis for Reversing Joint Damage
The field of arthritis research is always seeking to find treatments that can alleviate pain, inflammation, and joint damage. This study investigates the effects of etodolac, a nonsteroidal anti-inflammatory drug (NSAID), on established adjuvant arthritis in rats. The researchers used a model of arthritis in rats, a common approach to studying the disease in a controlled setting, to assess the potential of etodolac to reverse joint damage. It's like studying the effects of different types of vegetation in a desert environment to understand how they can thrive in a harsh climate.
Etodolac and Joint Damage: A Positive Sign in the Desert
The study found that etodolac was effective in reducing joint damage in rats with established adjuvant arthritis. This positive result is like discovering a hidden oasis in the desert. The authors concluded that etodolac can partially reverse joint damage in rats with established adjuvant arthritis, suggesting that it may have therapeutic potential in humans.
Living with Arthritis: Finding Relief in the Desert
While this study was conducted in rats, the findings provide hope for individuals with arthritis. It's important to consult with your doctor to discuss appropriate treatment options for your specific condition. NSAIDS, such as etodolac, may offer relief from pain and inflammation, but they can also have side effects. It's like choosing the right path in the desert - every decision has consequences.
Dr.Camel's Conclusion
The desert of arthritis research is vast and challenging. This study provides a glimmer of hope for those seeking relief from joint damage. While further research is needed to understand the full potential of etodolac in humans, it represents a promising step forward in the search for effective treatments.
Date :
- Date Completed 1987-06-05
- Date Revised 2019-07-18
Further Info :
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