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[1 percent clindamycin phosphate solution versus 5 percent benzoyl peroxide gel in papulopustular acne].

Author: FantaD, NeumannR, RaabW, SchmidtJ B

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Clindamycin phosphate and benzoyl peroxide were compared for their effectiveness in treating papulopustular acne. Both treatments showed comparable efficacy, but clindamycin phosphate was associated with significantly fewer side effects.
Paper Details　
Original Abstract of the Article :
In a multicenter study, 60 patients suffering from mainly moderate papulopustular acne were treated to pically either with 1% clindamycin phosphate in alcoholic solution or with 5% benzoyl peroxide gel, 30 patients each. During the treatment period of 9 weeks, clinical controls with lesion counts we...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2970159

データ提供：米国国立医学図書館（NLM）

Clindamycin Phosphate Versus Benzoyl Peroxide: Which Reigns Supreme in Acne Treatment?

Acne, a common skin condition, often leads to frustration and discomfort. This study aimed to compare the effectiveness of two popular topical treatments: clindamycin phosphate and benzoyl peroxide, in managing papulopustular acne. The researchers recruited 60 patients with moderate acne and randomly assigned them to receive either 1% clindamycin phosphate solution or 5% benzoyl peroxide gel. They carefully monitored the patients' progress over a period of nine weeks, meticulously recording the number of acne lesions.

Clindamycin Phosphate: A Promising Alternative

The results of this study showed that both clindamycin phosphate and benzoyl peroxide achieved similar levels of improvement in reducing papules and pustules. However, clindamycin phosphate was associated with significantly fewer side effects. This finding suggests that clindamycin phosphate could be a valuable alternative treatment option for acne, particularly for patients who experience adverse reactions to benzoyl peroxide.

Gentle Approaches to Skin Health

While both treatments proved effective, clindamycin phosphate's gentler nature makes it a more appealing option for individuals with sensitive skin. This study underscores the importance of finding the right treatment approach for each patient, considering their individual needs and preferences.

Dr. Camel's Conclusion

Think of acne like a stubborn sandstorm in the desert. Sometimes a strong wind (benzoyl peroxide) is needed to clear the air, but other times a more gentle approach (clindamycin phosphate) is preferable. This study suggests that clindamycin phosphate can effectively clear the acne 'sandstorm' without leaving a trail of irritation behind. Ultimately, the best treatment approach is the one that works best for you, so it's crucial to consult a dermatologist to find the solution that suits your individual skin needs.

Date :
  1. Date Completed 1988-09-21
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

2970159

DOI: Digital Object Identifier

2970159

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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