A randomized open-label study of guideline-driven antiemetic therapy versus single agent antiemetic therapy in patients with advanced cancer and nausea not related to anticancer treatment.

Author: CurrowDavid, GlarePaul, HardyJanet, HudsonPeter, MartinPeter, MitchellGeoffrey, PhilipJennifer, SkermanHelen, SpruytOdette, YatesPatsy

Paper Details 
Original Abstract of the Article :
Nausea/vomiting (N/V) not related to anti-cancer treatment is common in patients with advanced cancer. The standard approach to management is to define a dominant cause, and treat with an antiemetic selected through pathophysiologic knowledge of emetic pathways. High rates of N/V control have been r...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932901/

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Nausea: A Study on Antiemetic Therapy for Advanced Cancer

This research compares the effectiveness of guideline-driven antiemetic therapy versus single-agent antiemetic therapy in managing nausea and vomiting (N/V) in patients with advanced cancer. Imagine this study like a camel caravan navigating the desert of cancer, seeking to alleviate the debilitating symptoms of nausea and vomiting. The researchers investigated whether a more comprehensive approach to antiemetic therapy, following established guidelines, is more effective than using a single-agent approach.

Finding the Right Oasis for Nausea Relief

The study found that guideline-driven antiemetic therapy may be more effective than single-agent therapy in managing N/V in patients with advanced cancer. This finding suggests that a more comprehensive and individualized approach to antiemetic therapy, taking into account the underlying causes of nausea and vomiting, may be more beneficial for patients. It's like recognizing that the desert offers a variety of oases, each with its unique strengths and weaknesses, and choosing the right oasis is crucial for a successful journey.

Tailoring Antiemetic Therapy for Optimal Outcomes

This research highlights the importance of tailoring antiemetic therapy to meet the individual needs of patients with advanced cancer. It encourages a more proactive and personalized approach to managing N/V, taking into account factors such as the underlying cause of nausea, the patient's medical history, and their preferences. It's like understanding that each camel caravan has its own unique requirements for navigating the desert, and customizing the journey to meet these needs is crucial for success.

Dr. Camel's Conclusion

This study is like a camel caravan traversing the desert of cancer, seeking to find the best path to alleviate the debilitating symptoms of nausea and vomiting. It's a reminder that effective treatment requires a comprehensive and individualized approach, tailored to the unique needs of each patient.

Date :
  1. Date Completed 2019-02-13
  2. Date Revised 2019-02-15
Further Info :

Pubmed ID

29720113

DOI: Digital Object Identifier

PMC5932901

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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