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5-Nitroimidazole-derived Schiff bases and their copper(II) complexes exhibit potent antimicrobial activity against pathogenic anaerobic bacteria.
Author: BachiSofia M P S, BeraldoHeloisa, FariasLuiz M, FerencsMicael O, FerreiraJoão F G, FrancoLucas L, MagalhãesPaula P, OliveiraAlexandre A, OliveiraAna P A, SpezialiNivaldo L
Original Abstract of the Article :
In the present work a family of novel secnidazole-derived Schiff base compounds and their copper(II) complexes were synthesized. The antimicrobial activities of the compounds were evaluated against clinically important anaerobic bacterial strains. The compounds exhibited in vitro antibacterial activ...See full text at original site
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引用元:
https://doi.org/10.1007/s10534-018-0106-6
データ提供:米国国立医学図書館(NLM)
New Hope in the Fight Against Anaerobic Infections: 5-Nitroimidazole-Derived Schiff Bases
Anaerobic bacteria, a diverse group of microorganisms that thrive in oxygen-deprived environments, can cause a wide range of infections, posing a significant challenge for healthcare providers. This study investigates the antimicrobial potential of novel 5-nitroimidazole-derived Schiff bases and their copper(II) complexes against clinically important anaerobic bacteria. Researchers synthesized and evaluated the antimicrobial activity of these compounds, identifying promising candidates with potent activity against various anaerobic bacterial strains. The study's findings offer a potential avenue for the development of new antibacterial drugs to combat the growing threat of antibiotic resistance.Combating Antibiotic Resistance
The study highlights the effectiveness of 5-nitroimidazole-derived Schiff bases and their copper(II) complexes against a wide range of anaerobic bacteria. The researchers observed that coordination with copper(II) significantly enhanced the antibacterial activity of several compounds, offering a potential strategy for overcoming antibiotic resistance. These findings underscore the importance of developing novel antimicrobial agents to combat the growing threat of antibiotic resistance and ensure effective treatment of bacterial infections.Understanding the Impact of Antibiotic Resistance
Antibiotic resistance is a growing concern, with bacteria becoming increasingly resistant to conventional medications. It's crucial to understand the implications of this threat and take steps to prevent its spread. This includes using antibiotics responsibly, avoiding unnecessary prescriptions, and practicing good hygiene habits. By working together, we can combat antibiotic resistance and ensure the continued efficacy of these life-saving medications.Dr. Camel's Conclusion
This study offers a ray of hope in the fight against antibiotic resistance, exploring the promising antimicrobial potential of novel 5-nitroimidazole-derived Schiff bases. The research's focus on developing new drugs to combat anaerobic bacterial infections highlights the importance of ongoing research and innovation in the field of antimicrobial drug development. As a researcher who values the power of scientific discovery, I applaud this study's efforts to address the growing threat of antibiotic resistance and ensure effective treatment options for bacterial infections.Date :
- Date Completed 2019-08-06
- Date Revised 2019-08-06
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