Misoprostol for small bowel ulcers in patients with obscure bleeding taking aspirin and non-steroidal anti-inflammatory drugs (MASTERS): a randomised, double-blind, placebo-controlled, phase 3 trial.

Author: McCloskeyCaroline, McConnachieAlex, McSkimmingPaula, TahaAli S

Paper Details 
Original Abstract of the Article :
The incidence of obscure gastrointestinal bleeding, which originates from the small bowel and is mainly associated with the use of aspirin and non-steroidal anti-inflammatory drugs (NSAIDs), is rising. We assessed the efficacy and safety of misoprostol for the treatment of small bowel ulcers and ero...See full text at original site
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引用元:
https://doi.org/10.1016/S2468-1253(18)30119-5

データ提供:米国国立医学図書館(NLM)

Misoprostol for Small Bowel Ulcers in Patients with Obscure Bleeding: A Randomized Trial

This study, conducted in the field of gastroenterology, investigates the efficacy of misoprostol in treating small bowel ulcers and erosions in patients taking low-dose aspirin or NSAIDs with obscure gastrointestinal bleeding. It's like finding an oasis in a desert of gastrointestinal distress. The study uses a randomized, double-blind, placebo-controlled trial with 197 participants to assess the effectiveness and safety of misoprostol.

Misoprostol: A Potential Oasis for Small Bowel Ulcers

The results suggest that misoprostol may be a promising treatment option for small bowel ulcers and erosions. It's like discovering a spring of fresh water in a parched desert. The study found that misoprostol significantly reduced the number of patients experiencing a major gastrointestinal event.

Navigating Gastrointestinal Distress

The study provides valuable insights into the management of small bowel ulcers, a condition that can be particularly challenging to diagnose and treat. It's like finding a guide through a desert, providing clarity and direction. The researchers suggest that misoprostol may be a valuable tool in managing this condition, but further research is needed to understand its long-term effects.

Dr. Camel's Conclusion

This study suggests that misoprostol may provide a much-needed oasis for patients with small bowel ulcers and erosions. However, further research is essential to fully evaluate its long-term efficacy and safety.

Date :
  1. Date Completed 2019-02-06
  2. Date Revised 2019-02-15
Further Info :

Pubmed ID

29754836

DOI: Digital Object Identifier

10.1016/S2468-1253(18)30119-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

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