Pilot study of orphenadrine as a novel treatment for muscle cramps in patients with liver cirrhosis.

Author: Abd-ElsalamSherief, AliLobna A, AlkhalawanyWalaa, BadawiRehab, El-KallaFerial, ElemaryBerihan, ElfertAsem, ElzeftawyAsmaa, HanafyAmr, MosaadSamah

Paper Details 
Original Abstract of the Article :
BACKGROUND AND AIMS: Muscle cramps markedly affect the quality of life in cirrhotic patients with no available highly effective treatment. The aim of this study was to assess the safety and efficacy of orphenadrine in the treatment of muscle cramps in cirrhotic patients. METHODS: The study enrolled...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949967/

データ提供:米国国立医学図書館(NLM)

Muscle Cramps in Liver Cirrhosis: A Challenging Condition

Liver cirrhosis, a serious condition characterized by scarring of the liver, can significantly impact quality of life. Muscle cramps, a common symptom of liver cirrhosis, can cause pain, discomfort, and disruption to daily activities. This pilot study explores the potential of orphenadrine, a medication commonly used for muscle spasms, as a novel treatment for muscle cramps in patients with liver cirrhosis.

Think of a camel caravan traversing a vast desert, its members facing the arduous journey with grit and determination. Liver cirrhosis, like a persistent desert wind, can gradually weaken the camels, affecting their overall health and well-being. Muscle cramps, like sudden, painful thorns encountered along the way, can further disrupt their journey, causing discomfort and slowing their progress.

Orphenadrine: A Potential Solution

This study suggests that orphenadrine might be a safe and effective treatment for muscle cramps in patients with liver cirrhosis. The study found a significant reduction in the frequency of muscle cramps after treatment with orphenadrine, offering hope for improved quality of life for those suffering from this condition.

Navigating the Challenges of Liver Cirrhosis

This study provides valuable insights into the management of liver cirrhosis, highlighting the importance of addressing the various symptoms that impact patient well-being. As researchers continue to investigate the complex challenges of liver cirrhosis, we may discover more effective treatment options, making the journey through this condition more manageable and comfortable.

Dr.Camel's Conclusion

Managing liver cirrhosis is like navigating a challenging desert landscape. This study sheds light on a potential solution for muscle cramps, a common obstacle encountered on this journey. Orphenadrine, like a sturdy camel saddle, may provide relief and comfort, making the path ahead a little smoother.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

29774156

DOI: Digital Object Identifier

PMC5949967

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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