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Original Abstract of the Article :
Background There are a number of false myths about buprenorphine based on unconfirmed animal data, even from isolated animal organs, and early clinical research. These myths came into textbooks on pharmacology and pain about 30 years ago and have been difficult to eradicate. Animal models of pain an...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/29913911
データ提供:米国国立医学図書館(NLM)
Buprenorphine: A Powerful Tool Often Misunderstood
Buprenorphine, a potent opioid analgesic, has been a subject of much debate and misunderstanding, often based on outdated information from animal studies. This review aims to clarify misconceptions surrounding buprenorphine and provide a comprehensive overview of its pharmacodynamics and pharmacokinetics, emphasizing its unique properties and clinical utility. This study delves into the complexities of buprenorphine's actions, dispelling common myths and highlighting its potential benefits for treating chronic pain and opioid addiction.
Unraveling the Complexities of Buprenorphine
This review provides a comprehensive analysis of buprenorphine's unique pharmacodynamics and pharmacokinetics, emphasizing its ability to act on all four opioid receptors. It also highlights its slow onset and long offset properties, making it particularly well-suited for managing chronic pain, including neuropathic pain and cancer pain. The review underscores the importance of accurate understanding of buprenorphine's properties to ensure its effective and safe utilization in clinical practice.
Implications for Pain Management: A Promising Alternative for Chronic Pain
This review highlights the potential of buprenorphine as a valuable tool for managing chronic pain, especially neuropathic pain and cancer pain. Its unique properties, including its slow onset and long offset, make it a promising alternative to traditional opioid analgesics, offering a more controlled and effective approach to pain management. Just as a camel endures long journeys through the desert, buprenorphine provides sustained relief from chronic pain, offering hope for patients seeking long-term comfort.
Dr. Camel's Conclusion
This study serves as a valuable resource for healthcare professionals seeking to optimize the use of buprenorphine in clinical practice. By dispelling common myths and highlighting its unique properties, this review encourages a more informed and nuanced approach to utilizing this powerful analgesic. As a dedicated researcher, I am encouraged by the potential of buprenorphine to improve the lives of patients suffering from chronic pain and opioid addiction.
Date :
- Date Completed n.d.
- Date Revised 2019-11-20
Further Info :
Pubmed ID
DOI: Digital Object Identifier
/j/sjpain.2013.4.issue-3/j.sjpain.2013.05.004/j.sjpain.2013.05.004.xml
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English
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