Paper Details 
Original Abstract of the Article :
Background There are a number of false myths about buprenorphine based on unconfirmed animal data, even from isolated animal organs, and early clinical research. These myths came into textbooks on pharmacology and pain about 30 years ago and have been difficult to eradicate. Animal models of pain an...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/29913911

データ提供:米国国立医学図書館(NLM)

Buprenorphine: A Powerful Tool Often Misunderstood

Buprenorphine, a potent opioid analgesic, has been a subject of much debate and misunderstanding, often based on outdated information from animal studies. This review aims to clarify misconceptions surrounding buprenorphine and provide a comprehensive overview of its pharmacodynamics and pharmacokinetics, emphasizing its unique properties and clinical utility. This study delves into the complexities of buprenorphine's actions, dispelling common myths and highlighting its potential benefits for treating chronic pain and opioid addiction.

Unraveling the Complexities of Buprenorphine

This review provides a comprehensive analysis of buprenorphine's unique pharmacodynamics and pharmacokinetics, emphasizing its ability to act on all four opioid receptors. It also highlights its slow onset and long offset properties, making it particularly well-suited for managing chronic pain, including neuropathic pain and cancer pain. The review underscores the importance of accurate understanding of buprenorphine's properties to ensure its effective and safe utilization in clinical practice.

Implications for Pain Management: A Promising Alternative for Chronic Pain

This review highlights the potential of buprenorphine as a valuable tool for managing chronic pain, especially neuropathic pain and cancer pain. Its unique properties, including its slow onset and long offset, make it a promising alternative to traditional opioid analgesics, offering a more controlled and effective approach to pain management. Just as a camel endures long journeys through the desert, buprenorphine provides sustained relief from chronic pain, offering hope for patients seeking long-term comfort.

Dr. Camel's Conclusion

This study serves as a valuable resource for healthcare professionals seeking to optimize the use of buprenorphine in clinical practice. By dispelling common myths and highlighting its unique properties, this review encourages a more informed and nuanced approach to utilizing this powerful analgesic. As a dedicated researcher, I am encouraged by the potential of buprenorphine to improve the lives of patients suffering from chronic pain and opioid addiction.

Date :
  1. Date Completed n.d.
  2. Date Revised 2019-11-20
Further Info :

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PICO Info
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Languages

English

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