Paper Details

  1. Home
  2. Paper Details

Donepezil for dementia due to Alzheimer's disease.

Author: BirksJacqueline S, HarveyRichard J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Alzheimer's disease (AD) is the most common type of dementia in older adults. One approach to treat AD symptoms involves increasing levels of a brain chemical called acetylcholine by blocking the enzyme that breaks it down. Donepezil is one medication that does this. This is an updated review of previous research on this topic.
Paper Details　
Original Abstract of the Article :
Alzheimer's disease is the most common cause of dementia in older people. One approach to symptomatic treatment of Alzheimer's disease is to enhance cholinergic neurotransmission in the brain by blocking the action of the enzyme responsible for the breakdown of the neurotransmitter acetylcholine. Th...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513124/

データ提供：米国国立医学図書館（NLM）

Donepezil: A Treatment for Alzheimer's Disease

Alzheimer's disease is a challenging condition that affects millions worldwide. This review delves into the use of donepezil, a cholinesterase inhibitor, for the treatment of Alzheimer's disease. Cholinesterase inhibitors work by enhancing cholinergic neurotransmission in the brain, which is a key process affected by Alzheimer's disease.

The Role of Cholinesterase Inhibitors in Alzheimer's Treatment

Donepezil has been shown to provide symptomatic relief for patients with Alzheimer's disease, improving cognitive function and daily living activities. The review highlights the importance of cholinesterase inhibitors in managing the symptoms of Alzheimer's disease.

Finding Hope in the Desert of Alzheimer's

While there is currently no cure for Alzheimer's disease, donepezil provides a ray of hope for patients and their families. It helps to improve quality of life and manage the symptoms of this debilitating condition.

Dr.Camel's Conclusion

Alzheimer's disease can feel like a vast, unforgiving desert, but donepezil offers a glimmer of hope. This medication helps to manage symptoms and improve quality of life for those living with Alzheimer's disease. It's a reminder that even in the most challenging situations, there can be ways to find relief and support.

Date :
  1. Date Completed 2018-08-14
  2. Date Revised 2023-10-11
Further Info :

Pubmed ID

29923184

DOI: Digital Object Identifier

PMC6513124

Related Literature

Article Analysis
・Effective treatment of alzheimer's disease
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.