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[Similarity of Clinically Significant Neuropsychiatric Adverse Reactions Listed in Package Inserts between the Anti-influenza Drugs Oseltamivir and Amantadine (Possibility Attributable to Common Pharmacological Effects)].

Author: FukushimaAkihiro, OkamuraMaya, OnoHideki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Oseltamivir, an anti-influenza virus drug, may induce neuropsychiatric side effects similar to those of amantadine and ester-type local anesthetics, potentially due to shared pharmacological actions.
Paper Details　
Original Abstract of the Article :
The anti-influenza virus drug oseltamivir has been reported to have several pharmacological actions including blocking of nicotinic acetylcholine receptor channels and activation of the dopaminergic system. These pharmacological actions highly overlap those of amantadine, another anti-influenza viru...See full text at original site
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引用元：
https://doi.org/10.1248/yakushi.18-00022

データ提供：米国国立医学図書館（NLM）

Unmasking the Mystery of Neuropsychiatric Side Effects: Oseltamivir and Amantadine

Venturing into the vast landscape of drug interactions is akin to navigating a desert with hidden dangers. This research explores the similarities in neuropsychiatric side effects between two anti-influenza medications, oseltamivir and amantadine. The authors propose that these shared side effects may be due to overlapping pharmacological actions, specifically their effects on the brain's chemical messengers. Their findings highlight the importance of carefully evaluating potential drug interactions.

Navigating Drug Interactions: A Cautionary Tale

The study reveals a potential link between the pharmacological actions of oseltamivir and amantadine and the occurrence of similar neuropsychiatric side effects. This underscores the importance of careful consideration of drug interactions and the need for comprehensive monitoring of patients taking these medications. It's like navigating a desert landscape where seemingly innocuous plants can hold dangerous secrets.

Navigating Medication Choices: Consult with Your Healthcare Provider

While this study highlights potential risks associated with certain medications, it's essential to consult with a healthcare professional for personalized guidance. They can assess your individual needs and help you make informed decisions about your medication choices.

Dr.Camel's Conclusion

This research delves into the complexities of drug interactions, reminding us that even seemingly unrelated medications can have shared side effects. It emphasizes the importance of vigilant monitoring and careful consideration of potential risks when prescribing and taking medications. Like a wise camel navigating a desert, it's essential to be aware of the potential dangers and seek guidance from experienced guides.

Date :
  1. Date Completed 2018-09-26
  2. Date Revised 2018-09-26
Further Info :

Pubmed ID

29925727

DOI: Digital Object Identifier

10.1248/yakushi.18-00022

SNS
PICO Info
in preparation
Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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