Paper Details

  1. Home
  2. Paper Details

The Hepatitis C-Alcohol Reduction Treatment (Hep ART) intervention: Study protocol of a multi-center randomized controlled trial.

Author: DattaSantanu K, EvonDonna M, FriedMichael W, HodgeTerra, MakarushkaChristina, MannelliPaolo, MuirAndrew J, NaggieSusanna, NiedzwieckiDonna, PatkarAshwin A, Proeschold-BellRae Jean, WilderJulius M, WongJohn B, YaoJia

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Clinical Trial ProtocolA plan for conducting a clinical trial. It describes in detail the purpose, design, methodology, and statistical considerations of the trial, ensuring the transparency and consistency of the trial.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

For people with hepatitis C virus (HCV) infection, alcohol use significantly increases the risk of liver damage, liver cancer, and death. While research suggests combining treatment for HCV and alcohol use may be helpful, studies have only been done in people with severe alcohol problems.
Paper Details　
Original Abstract of the Article :
Among patients with hepatitis C virus (HCV) infection, alcohol synergistically increases the risk of cirrhosis, hepatocellular carcinoma, and death. Randomized controlled trials of integrated models of HCV-alcohol treatment have been recommended but only performed in patients with severe alcohol use...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/30006024

データ提供：米国国立医学図書館（NLM）

Hepatitis C and Alcohol: A Collaborative Approach to Treatment

The battle against hepatitis C virus (HCV) infection is a complex and ongoing one, with researchers striving to find effective treatments and manage the risks associated with this chronic disease. This study focuses on the synergistic effect of alcohol use on the severity of HCV infection, highlighting the need for integrated models of treatment that address both conditions simultaneously. The authors propose a multi-center randomized controlled trial, known as the Hepatitis C-Alcohol Reduction Treatment (Hep ART) intervention, which aims to evaluate the effectiveness of this integrated approach.

Integrated Treatment for HCV and Alcohol Use: A Collaborative Approach

The study aims to investigate the efficacy of a comprehensive treatment approach that addresses both HCV infection and alcohol use disorders, recognizing that these two conditions often go hand in hand. This research, like a desert traveler seeking a source of water and sustenance, highlights the importance of addressing multiple health challenges simultaneously for optimal patient outcomes.

Optimizing Treatment Strategies: A Multifaceted Approach to HCV Management

This research emphasizes the need for a holistic approach to managing HCV infection, considering the co-occurrence of alcohol use disorders and the potential for synergistic effects on disease progression. The Hep ART intervention offers a promising model for integrated treatment, potentially leading to improved patient outcomes and a greater chance of achieving sustained viral suppression.

Dr.Camel's Conclusion

This study underscores the importance of developing integrated treatment approaches for HCV infection, particularly in the context of co-occurring alcohol use disorders. The proposed Hep ART intervention, with its focus on a collaborative approach to treatment, offers a promising avenue for improving patient outcomes and addressing the multifaceted challenges associated with HCV infection. This research encourages continued exploration of multidisciplinary strategies for managing chronic diseases, recognizing the need for tailored and comprehensive care that addresses the individual needs of patients.

Date :
  1. Date Completed 2019-12-02
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

30006024

DOI: Digital Object Identifier

NIHMS1044408

Related Literature

Article Analysis
・Effective treatment of hepatitis c
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.