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Evaluation of the efficacy of transdermal drug delivery of calcipotriol plus betamethasone versus tacrolimus in the treatment of vitiligo.

Author: Al-ShenawyHanan A, ElgendyHoda Y, HassanGhada F, IbrahimZeinab A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This article discusses the use of microneedling for treating vitiligo. Microneedling is an evolving technique that involves creating pores in the stratum corneum to augment transdermal drug delivery.
Paper Details　
Original Abstract of the Article :
Vitiligo is a common pigmentary disorder affecting about 1% of the general population. There are numerous medical and surgical treatments. Microneedling is an evolving treatment technique for an expanding number of dermatologic conditions. It is used also to augment transdermal drug delivery through...See full text at original site
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引用元：
https://doi.org/10.1111/jocd.12704

データ提供：米国国立医学図書館（NLM）

Transdermal Drug Delivery in Vitiligo: A New Approach to Treatment

Vitiligo, a disorder that creates patches of depigmentation on the skin like a map of lost color in a desert landscape, is a challenging condition to treat. This study explores the efficacy of transdermal drug delivery, a technique that transports medication through the skin like a caravan crossing a vast expanse, using a combination of calcipotriol and betamethasone compared to tacrolimus. The researchers investigated the potential of microneedling, a process that creates tiny channels in the skin, to enhance the delivery of these medications.

A Journey Through the Skin: Microneedling for Vitiligo Treatment

The study found that transdermal drug delivery using microneedling, while a promising approach, did not yield conclusive results regarding its effectiveness in treating vitiligo. The researchers found that this novel approach, while promising, requires further exploration to fully understand its potential in treating vitiligo.

Navigating the Desert of Skin Disorders: A Search for Effective Treatments

Vitiligo can have a profound impact on a person's self-esteem and overall well-being. This study highlights the ongoing search for effective and minimally invasive treatments. The researchers acknowledge the need for further research to fully understand the potential of microneedling and transdermal drug delivery in treating vitiligo.

Dr. Camel's Conclusion

Vitiligo, a condition that can leave the skin looking like a scattered tapestry of colors, is a difficult journey to navigate. This study delves into the potential of a new approach: transdermal drug delivery with microneedling. While the researchers found promise, further exploration is needed to fully understand its effectiveness. We continue to search for new solutions in the vast desert of skin disorders, seeking to restore harmony to the skin's landscape.
Date :
  1. Date Completed 2020-01-14
  2. Date Revised 2020-01-14
Further Info :

Pubmed ID

30009490

DOI: Digital Object Identifier

10.1111/jocd.12704

Related Literature

Article Analysis
・Side Effects of calcitriol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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