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Impact of Prior Local Treatment on the Outcomes of Metastatic Hormone-Sensitive Prostate Cancer: Secondary Analysis of a Randomized Controlled Trial.

Author: Abdel-RahmanOmar, CheungWinson Y

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Patients with metastatic hormone-sensitive prostate cancer and prior local treatment had better overall survival, progression-free survival, and cancer-specific survival compared to those without prior local treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Local treatment of metastatic prostate cancer and its impact on future disease course requires further assessment. We sought to evaluate the impact of prior local treatment to the prostate on the outcomes of hormone-sensitive prostate cancer (HSPC) patients recruited in the CHAARTED stud...See full text at original site
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引用元：
https://doi.org/10.1016/j.clgc.2018.07.007

データ提供：米国国立医学図書館（NLM）

Investigating the Impact of Local Treatment on Metastatic Prostate Cancer

This study looks at the impact of local treatment on the course of metastatic hormone-sensitive prostate cancer (HSPC). Researchers analyzed data from a large clinical trial (CHAARTED) to understand how prior local treatment to the prostate affects patient outcomes. The study aims to provide evidence-based insights into the role of local treatment in managing this complex disease.

Prior Local Treatment Shows Promise for Metastatic Prostate Cancer

The analysis revealed a positive association between prior local treatment and improved overall survival, progression-free survival, and cancer-specific survival in men with metastatic HSPC. These findings suggest that local treatment could play a valuable role in managing the disease.

Rethinking Treatment Strategies for Metastatic Prostate Cancer

This study highlights the potential benefits of incorporating local treatment into the management of metastatic HSPC. It provides a strong rationale for further investigation and consideration of this approach in clinical practice.

Dr. Camel's Conclusion

Like a wise old camel navigating the shifting sands of medical knowledge, this study offers a new perspective on treating metastatic prostate cancer. The findings point to the importance of local treatment and offer hope for improved outcomes for patients facing this challenging diagnosis.

Date :
  1. Date Completed 2019-06-24
  2. Date Revised 2019-06-24
Further Info :

Pubmed ID

30098982

DOI: Digital Object Identifier

10.1016/j.clgc.2018.07.007

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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