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Prophylactic and therapeutic effects of twice-daily famciclovir administration on infectious upper respiratory disease in shelter-housed cats.

Author: CooperAnn E, DrazenovichTracy L, KassPhilip H, LeuteneggerChristian M, MaggsDavid J, PotnisSanskruti S, ThomasySara M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled Trial, VeterinaryRandomized controlled trials involving animals. They evaluate the efficacy and safety of treatment methods.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Famciclovir administration at 30 or 90 mg/kg q12h for 1 week reduced conjunctival FHV-1 shedding in cats with herpetic disease, suggesting a potential role in interrupting the infectious cycle within a shelter population.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: In humans with herpetic disease, early or pre-emptive famciclovir therapy reduces disease duration and severity. This prospective, masked, placebo-controlled study tested therapeutic and prophylactic effects of two famciclovir doses given to cats for 7 days following shelter entry. METH...See full text at original site
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引用元：
https://doi.org/10.1177/1098612X18789719

データ提供：米国国立医学図書館（NLM）

Famciclovir: A Potential Weapon Against Feline Herpesvirus

This research ventures into the fascinating realm of [veterinary medicine] and investigates [the prophylactic and therapeutic effects of famciclovir] on [infectious upper respiratory disease] in [shelter-housed cats]. Utilizing a [prospective, masked, placebo-controlled study], the authors examined [the efficacy of famciclovir] in [reducing viral shedding] in [cats with feline herpesvirus infection]. The findings suggest that [famciclovir] may play a role in [interrupting the infectious cycle] within a [shelter population], although [cost and stress considerations] need to be taken into account.

Viral Shedding: A Silent Threat

The study revealed that [famciclovir] significantly reduced [conjunctival feline herpesvirus 1 shedding] in [cats] receiving the drug. This is significant because [viral shedding] can spread [infection] to other [cats] in a [shelter environment].

Shelter Cats: A Need for Prevention

Given the potential role of [famciclovir] in [reducing viral shedding], it could be a valuable tool for [preventing and managing feline herpesvirus infection] in [shelter cats]. However, it's essential to carefully weigh the [costs and benefits] before implementing [famciclovir] as a standard practice in [shelters].

Dr. Camel's Conclusion

This research offers valuable insights into the challenges faced by [shelter cats] and the potential of [famciclovir] to mitigate the spread of [feline herpesvirus]. While [famciclovir] shows promise, further research is needed to optimize its use and ensure its effectiveness and safety in [shelter environments].

Date :
  1. Date Completed 2020-06-22
  2. Date Revised 2020-06-22
Further Info :

Pubmed ID

30099962

DOI: Digital Object Identifier

10.1177/1098612X18789719

Related Literature

Article Analysis
・Effects of famciclovir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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