Paper Details

  1. Home
  2. Paper Details

WITHDRAWN: Topical and systemic antifungal therapy for the symptomatic treatment of chronic rhinosinusitis.

Author: GallagherRichard M, HarveyRichard J, RimmerJanet, SacksPeta-Lee, SacksRaymond

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A review of the use of antifungal agents for chronic rhinosinusitis (CRS) found that although fungi may play a role in CRS, there is no clear evidence that antifungal agents are effective in its management.
Paper Details　
Original Abstract of the Article :
Chronic rhinosinusitis (CRS) is an inflammatory disorder of the nose and sinuses. Since fungi were postulated as a potential cause of CRS in the late 1990s, there has been increasing controversy about the use of both topical and systemic antifungal agents in its management. Although interaction betw...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513541/

データ提供：米国国立医学図書館（NLM）

Fungal Mystery in Chronic Rhinosinusitis

In the world of otolaryngology, researchers are continuously seeking to understand the complexities of chronic rhinosinusitis (CRS). This study delves into the controversial role of fungi in the development and treatment of this condition. The authors explore the effectiveness of both topical and systemic antifungal agents in managing CRS.

Debunking the Fungus-CRS Link

While there's evidence of an interaction between the immune system and fungi in CRS, the study cautions against attributing the cause of CRS to fungi alone. The researchers suggest that while antifungals might play a role in some cases, they may not be a universally effective treatment for CRS. Think of it as a desert oasis - while water is essential for survival, it's not the only factor contributing to the oasis's thriving ecosystem.

More Research Needed

This study highlights the need for further research to understand the complex interplay between fungi, the immune system, and CRS. It emphasizes the importance of a multifaceted approach to managing CRS, considering factors beyond just the presence of fungi. Remember, the desert is a complex environment, and understanding its intricacies is crucial for navigating it successfully.

Dr. Camel's Conclusion

The study reminds us that the world of medicine is full of intricate puzzles. While fungi may be a factor in CRS, they may not be the sole culprit. It emphasizes the need for a comprehensive approach to treating this condition, considering the complex interplay between various factors. It's like navigating a desert - we need to consider the entire ecosystem, not just one element, to find the right path to wellness.

Date :
  1. Date Completed 2018-10-24
  2. Date Revised 2023-11-15
Further Info :

Pubmed ID

30184244

DOI: Digital Object Identifier

PMC6513541

Related Literature

Article Analysis
・Effective treatment of sinusitis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.