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Nebulized Corticosteroids in the Treatment of COPD Exacerbations: Systematic Review, Meta-Analysis, and Clinical Perspective.

Author: BeiHe, BeikoTatsiana, DrummondM Bradley, PleasantsRoy A, WangTiansheng, XuXiaohan, ZhaiSuodi

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

High-dose nebulized budesonide was noninferior to systemic corticosteroids for the treatment of COPD exacerbations.
Paper Details　
Original Abstract of the Article :
BACKGROUND: COPD guidelines report that systemic corticosteroids are preferred over inhaled corticosteroids in the treatment of exacerbations, but the inhaled route is considered to be an option. OBJECTIVES: To conduct a systematic review and meta-analysis regarding the efficacy and safety of inhal...See full text at original site
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引用元：
https://doi.org/10.4187/respcare.06384

データ提供：米国国立医学図書館（NLM）

Inhaled Corticosteroids for COPD Exacerbations: A New Perspective

This comprehensive study evaluates the efficacy and safety of inhaled corticosteroids in the treatment of COPD exacerbations. The researchers conducted a systematic review and meta-analysis of existing research, focusing on the change in forced expiratory volume in one second (FEV1) as a primary outcome measure. The study found that high-dose nebulized budesonide was non-inferior to systemic corticosteroids in improving lung function. The study also provides a detailed pharmacologic and clinical perspective on the use of inhaled corticosteroids for COPD exacerbations.

Inhaled Corticosteroids: A Potential Alternative

This study suggests that inhaled corticosteroids, specifically nebulized budesonide, can be a viable alternative to systemic corticosteroids in managing COPD exacerbations. The study's findings contribute to a better understanding of the potential benefits and risks of inhaled corticosteroids for COPD patients.

COPD: A Camel's Journey Through Dusty Air

As a camel, I've learned to navigate dusty environments, much like those faced by individuals with COPD. This study highlights the importance of effective treatments for COPD exacerbations, suggesting that inhaled corticosteroids may offer a valuable alternative for managing this condition.

Dr.Camel's Conclusion

This study provides valuable insights into the use of inhaled corticosteroids for COPD exacerbations, offering evidence that nebulized budesonide can be a viable alternative to systemic corticosteroids. The study's findings contribute to a growing understanding of the potential benefits and risks of inhaled corticosteroids in managing COPD.
Date :
  1. Date Completed 2019-09-30
  2. Date Revised 2019-09-30
Further Info :

Pubmed ID

30237276

DOI: Digital Object Identifier

10.4187/respcare.06384

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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