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Association between Neuropsychiatric Improvement and Neurocognitive Change in Alzheimer's Disease: Analysis of the CATIE-AD Study.
Author: MimuraMasaru, NagataTomoyuki, NakajimaShinichiro, ShigetaMasahiro, ShinagawaShunichiro
Original Abstract of the Article :
BACKGROUND/OBJECTIVE: To assess associations between improvements in neuropsychiatric symptoms (NPS) and neurocognitive change in patients with Alzheimer's disease (AD) during treatment using the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer Disease (CATIE-AD) dataset. METHO...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.3233/JAD-180304
データ提供:米国国立医学図書館(NLM)
Neuropsychiatric Improvement and Neurocognitive Change in Alzheimer's Disease
This study delves into the complex world of Alzheimer's disease (AD), exploring the relationship between neuropsychiatric symptoms (NPS) and neurocognitive decline. The researchers, like intrepid explorers navigating a treacherous desert, sought to uncover the intricate connections between these two aspects of AD. Their findings suggest that neurocognitive preservation may be associated with improved neuropsychiatric outcomes, offering a glimmer of hope in the challenging landscape of this debilitating disease.
Neurocognitive Preservation May Be Associated with Improved NPS
The study found that improvement in NPS was significantly associated with baseline severity of psychotic symptoms and a lesser decline in neurocognitive function. This is a valuable discovery, akin to finding a hidden oasis in the parched landscape of AD. This research suggests that strategies aimed at preserving cognitive function may also play a role in mitigating neuropsychiatric symptoms, offering a multipronged approach to managing AD.
Managing Neuropsychiatric Symptoms in Alzheimer's Disease
This research highlights the crucial connection between neurocognitive function and neuropsychiatric symptoms in AD. It's like discovering a vital trade route in a vast desert, demonstrating the interdependence of different aspects of the disease. This study underscores the importance of comprehensive management strategies that address both cognitive and psychiatric challenges, offering a more holistic approach to managing AD.
Dr. Camel's Conclusion
This study offers valuable insights into the relationship between neuropsychiatric symptoms and neurocognitive decline in AD. It's like finding a hidden oasis in the vast desert of Alzheimer's research, providing a glimmer of hope for those seeking ways to manage this debilitating disease. The researchers' findings suggest that strategies aimed at preserving cognitive function may also play a role in improving neuropsychiatric outcomes, offering a multipronged approach to managing AD.
Date :
- Date Completed 2019-09-18
- Date Revised 2019-09-18
Further Info :
Related Literature
English
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