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Preventive effect of cyproheptadine on sleep and appetite disorders induced by methylphenidate: an exploratory randomised, double-blinded, placebo-controlled clinical trial.

Author: ElyasiSepideh, Kadkhoda MezerjiFaezeh, MohammadpourAmir Hooshang, MoharreriFatemeh

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This research evaluates the preventive effects of cyproheptadine on sleeping and appetite disorders induced by methylphenidate in children with attention deficit/hyperactivity disorder (ADHD). Methylphenidate, a common ADHD medication, can cause insomnia and loss of appetite, leading to non-compliance and treatment discontinuation. The study aimed to determine if cyproheptadine could prevent these side effects.
Paper Details　
Original Abstract of the Article :
Insomnia and loss of appetite are the most common side effects of methylphenidate in patients with attention deficit/hyperactivity disorder (ADHD). The adverse effects may limit optimal dosing and patients' compliance with treatment leading to the discontinuation of treatment. This research evaluate...See full text at original site
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引用元：
https://doi.org/10.1080/13651501.2018.1509095

データ提供：米国国立医学図書館（NLM）

Cyproheptadine: A Potential Solution for Methylphenidate Side Effects

This study examines the potential of cyproheptadine, an antihistamine, to prevent insomnia and loss of appetite, common side effects of methylphenidate, a medication often used to treat attention deficit/hyperactivity disorder (ADHD). The study found that cyproheptadine may be effective in preventing these side effects, potentially leading to improved patient compliance with methylphenidate treatment. This could be particularly helpful for children with ADHD who struggle with the side effects of methylphenidate.

Cyproheptadine: A Potential Solution for ADHD Side Effects

The study suggests that cyproheptadine may be a promising tool for preventing insomnia and loss of appetite, common side effects of methylphenidate. This finding could significantly improve the lives of children with ADHD who struggle with these side effects.

Managing ADHD and its Side Effects

This study highlights the importance of considering the potential side effects of ADHD medications and finding strategies to minimize them. Parents should be aware of these side effects and talk to their child's doctor if they experience any difficulties.

Dr.Camel's Conclusion

Just as a camel's thick eyelashes protect its eyes from the harsh desert sun, cyproheptadine might offer a protective shield against the side effects of methylphenidate. This study suggests that this medication might be a valuable tool for improving the lives of children with ADHD.

Date :
  1. Date Completed 2019-11-19
  2. Date Revised 2019-11-19
Further Info :

Pubmed ID

30261781

DOI: Digital Object Identifier

10.1080/13651501.2018.1509095

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・Side Effects of cyproheptadine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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