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Everolimus-induced pulmonary toxicity: Findings on 18F-FDG PET/CT imaging.

Author: Bruna-MurailleClaire, DejustSebastien, EymardJean-Christophe, MorlandDavid, PapathanassiouDimitri, SavoyeAude-Marie, YazbekGabriel

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

This retrospective study investigated the frequency and imaging characteristics of everolimus lung side effects on F-FDG PET/CT in patients with metastatic breast cancer treated with the everolimus-exemestane combination. The study found that pleuroparenchymal anomalies were detected in 62% of patients, with alveolar-interstitial lesions being the most common. The number of segments involved was significantly higher in patients with severe pneumopathy.
Paper Details　
Original Abstract of the Article :
The everolimus-exemestane combination is indicated in advanced breast cancer treatment and usually well tolerated. The objective of the study was to determine the frequency of everolimus lung side effects and investigate their imaging characteristics on positron emission tomography with 18F-fluoro-d...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200531/

データ提供：米国国立医学図書館（NLM）

Everolimus-Induced Pulmonary Toxicity: Insights from F-FDG PET/CT Imaging

This research explores the potential side effects of everolimus, a medication used in advanced breast cancer treatment, on the lungs. The study employed F-FDG PET/CT imaging to investigate the frequency and imaging characteristics of everolimus-induced pulmonary toxicity in patients with metastatic breast cancer. The results reveal a significant prevalence of lung abnormalities, mainly alveolar-interstitial lesions, in patients receiving everolimus treatment. The study highlights the importance of monitoring for these potential side effects and underscores the value of F-FDG PET/CT imaging in detecting and characterizing these changes.

Imaging Lung Toxicity: A Visual Guide to Everolimus Side Effects

This study, like a skilled cartographer mapping a vast desert, provides a detailed map of the potential pulmonary side effects associated with everolimus treatment. The research highlights the valuable role of F-FDG PET/CT imaging in detecting and characterizing these changes, offering a visual guide for healthcare providers to monitor for and manage this potential complication.

Navigating Cancer Treatment: A Holistic Approach

The research underscores the importance of a holistic approach to cancer treatment, including careful monitoring for potential side effects. By employing imaging techniques like F-FDG PET/CT, healthcare providers can detect and manage potential complications, improving the overall treatment experience for patients.

Dr.Camel's Conclusion

Just as a desert traveler carefully navigates the changing landscape, this research offers a roadmap to understanding and managing everolimus-induced pulmonary toxicity. The study highlights the value of F-FDG PET/CT imaging in detecting and characterizing these changes, providing valuable insights for healthcare providers to ensure the safety and well-being of patients undergoing everolimus treatment.
Date :
  1. Date Completed 2018-10-23
  2. Date Revised 2022-10-05
Further Info :

Pubmed ID

30290608

DOI: Digital Object Identifier

PMC6200531

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Languages

English

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