Paper Details

  1. Home
  2. Paper Details

Is bran efficacious in irritable bowel syndrome? A double blind placebo controlled crossover study.

Author: ClarkM L, DawsonA M, LowndesJ, LuceyM R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study of 28 patients with irritable bowel syndrome found that bran biscuits did not provide any significant benefit compared to placebo biscuits, despite a placebo effect being observed in both groups.
Paper Details　
Original Abstract of the Article :
Twenty eight patients with classical irritable bowel syndrome completed a double blind placebo controlled crossover trial in which they added to their normal diet a daily supplement of either 12 bran biscuits (1 = 1.3 g fibre) or 12 placebo biscuits (1 = 0.23 g fibre). Each biscuit was given for thr...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1136/gut.28.2.221

データ提供：米国国立医学図書館（NLM）

Bran and Irritable Bowel Syndrome: A Tale of Placebo and Fiber

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits. This research, published in Gut, investigates the efficacy of bran in treating IBS symptoms. The study, conducted in 28 patients with IBS, found that while both bran and placebo groups showed significant improvement in symptoms, there was no significant difference between the two groups. The authors conclude that the beneficial effects of bran in IBS are likely due to a placebo response, independent of any increase in stool weight.

A Desert of Discomfort: Navigating the Complexities of IBS

This research explores the complex nature of IBS, highlighting the potential role of placebo effects in symptom management. The authors' findings suggest that while dietary interventions like increasing fiber intake may be helpful, the placebo response may play a significant role in the perceived benefits. This emphasizes the need for a holistic approach to IBS management.

Finding Relief in the Desert: A Holistic Approach to IBS

This study offers valuable insights into the treatment of IBS, suggesting that a multi-faceted approach, incorporating lifestyle changes, dietary adjustments, and addressing the psychological aspects of the condition, may be more effective than relying solely on dietary interventions. Patients with IBS should work with their healthcare provider to develop a personalized management plan that addresses their individual needs.

Dr. Camel's Conclusion

IBS can feel like an endless, dusty desert, but this research reminds us that the journey to relief can be a complex one. While dietary interventions like increasing fiber intake may be helpful, the placebo effect, like a desert oasis, can offer temporary relief. This research emphasizes the importance of a holistic approach to managing IBS, addressing the psychological aspects alongside the physical symptoms.
Date :
  1. Date Completed 1987-05-11
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

3030904

DOI: Digital Object Identifier

10.1136/gut.28.2.221

Related Literature

Article Analysis
・Effective treatment of irritable bowel syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.