Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine Against Invasive Disease Caused by Serotype 3 in Children: A Systematic Review and Meta-analysis of Observational Studies.

Author: De WalsPhilippe, GessnerBradford D, IsturizRaul, JodarLuis, LaferriereCraig, McLaughlinJohn M, PeltonStephen, SchmittHeinz-Josef, SingsHeather L, SuayaJose A

Paper Details 
Original Abstract of the Article :
The 13-valent pneumococcal conjugate vaccine (PCV13) is the only licensed PCV with serotype 3 polysaccharide in its formulation. Postlicensure PCV13 effectiveness studies against serotype 3 invasive pneumococcal disease (IPD) in children have shown inconsistent results.  We performed a systematic re...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541704/

データ提供:米国国立医学図書館(NLM)

13-Valent Pneumococcal Conjugate Vaccine: A Shield Against Invasive Disease

In the ongoing battle against invasive pneumococcal disease (IPD), the 13-valent pneumococcal conjugate vaccine (PCV13) stands as a formidable weapon. This study, like a caravan carefully navigating a treacherous desert path, aimed to assess the effectiveness of PCV13 in protecting children against serotype 3 IPD. The researchers meticulously examined the available data, drawing on a systematic review and meta-analysis of observational studies.

The researchers, like explorers charting a course through an uncharted desert, encountered inconsistencies in previous studies, leading them to embark on a comprehensive analysis to provide a clearer understanding of the vaccine's effectiveness.

A Promising Shield Against Invasive Disease

The study found that PCV13 demonstrated a pooled vaccine effectiveness (VE) of 63.5% against serotype 3 IPD in children. This finding, like a beacon in the desert, offers encouraging evidence of the vaccine's protective efficacy, providing a shield against the devastating effects of IPD.

The Power of Vaccination

This study highlights the crucial role of vaccination in protecting children from preventable diseases. It's a reminder that vaccination is an essential tool, like a camel's hump storing vital resources, for safeguarding health and well-being. By embracing vaccination, we can create a healthier future for our children and build a more resilient society.

Dr. Camel's Conclusion

This study, like a desert oasis offering respite from the scorching sun, provides a valuable resource for understanding the effectiveness of PCV13 against serotype 3 IPD in children. The findings reinforce the importance of vaccination in preventing serious diseases and highlight the potential of this vaccine to protect our most vulnerable citizens.

Date :
  1. Date Completed 2020-07-28
  2. Date Revised 2021-05-04
Further Info :

Pubmed ID

30357326

DOI: Digital Object Identifier

PMC6541704

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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