Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin.

Author: Al-JamalKhuloud T, BackholmMatilda, FanLi, KettunenMikko I, LehtoVesa-Pekka, NissinenTuomo, NäkkiSimo, RantanenJimi, RasRobin H A, WangJulie T-W, WuJianwei, XuWujun

Paper Details 
Original Abstract of the Article :
The inability of traditional chemotherapeutics to reach cancer tissue reduces the treatment efficacy and leads to adverse effects. A multifunctional nanovector was developed consisting of porous silicon, superparamagnetic iron oxide, calcium carbonate, doxorubicin and polyethylene glycol. The partic...See full text at original site
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引用元:
https://doi.org/10.1016/j.ijpharm.2018.10.074

データ提供:米国国立医学図書館(NLM)

Nanotechnology: A Promising Approach for Cancer Treatment

The fight against cancer is constantly evolving, and the field of nanotechnology is emerging as a powerful tool for developing novel treatments. This study explores the potential of a multifunctional nanovector for delivering chemotherapy drugs directly to tumor tissues, reducing side effects and improving treatment efficacy. The authors developed a porous silicon-based nanoparticle that incorporates magnetic properties, drug-carrying capacity, and pH-controlled drug release. Their research demonstrates the promising potential of this nanovector for both cancer monitoring and therapy.

Nanovectors Offer Targeted Delivery

The study found that the nanovector effectively delivered doxorubicin to tumor tissues, significantly reducing side effects and achieving comparable anti-tumor effects to free doxorubicin. This highlights the potential of nanotechnology to overcome the limitations of traditional chemotherapy, where drugs often cause significant damage to healthy tissues.

Nanotechnology Holds Promise for Future Cancer Treatments

This research represents a significant step forward in the development of targeted drug delivery systems for cancer therapy. The multifunctional nanovector, with its magnetic properties, drug-carrying capacity, and pH-controlled release, provides a promising platform for future research and development.

Dr.Camel's Conclusion

The world of nanotechnology is a vast and exciting landscape, and this research shows the potential for nanovectors to revolutionize cancer treatment. Like a camel navigating the shifting sands of the desert, researchers are constantly exploring new pathways to overcome the challenges of cancer. This research offers a glimpse into the future of cancer treatment, where targeted delivery systems could significantly improve patient outcomes.

Date :
  1. Date Completed 2019-04-03
  2. Date Revised 2022-01-29
Further Info :

Pubmed ID

30391665

DOI: Digital Object Identifier

10.1016/j.ijpharm.2018.10.074

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SNS
PICO Info
in preparation
Languages

English

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