Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide as a combination therapy for chronic obstructive pulmonary disease.

Author: KunaPiotr, KupczykMaciej

Paper Details 
Original Abstract of the Article :
The triple therapy term covers the combination of inhaled corticosteroid (ICS), long-acting β-receptor agonist (LABA) and long-acting anticholinergic drug (LAMA) in one or in separate inhalers. The latest GOLD 2018 (Global Initiative for Chronic Obstructive Disease) guidelines recommend the triple t...See full text at original site
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引用元:
https://doi.org/10.1080/17476348.2019.1548937

データ提供:米国国立医学図書館(NLM)

The Triple Therapy Approach to Chronic Obstructive Pulmonary Disease (COPD)

COPD, a chronic lung disease, can significantly impact a person's quality of life. This study investigates the efficacy of a triple therapy combination for managing COPD, combining inhaled corticosteroids (ICS), long-acting β-receptor agonists (LABA), and long-acting anticholinergic drugs (LAMA) in a single inhaler. The research team explored the pharmacokinetic and pharmacodynamic properties, clinical efficacy, and safety profile of this triple combination therapy in patients with COPD.

The results showed a significant reduction in the risk of moderate or severe COPD exacerbations in patients receiving the triple therapy compared to dual therapies like ICS/LABA or LAMA monotherapy. This triple therapy also reduced the number of exacerbations compared to double bronchodilatation (LABA/LAMA) making it a promising therapeutic option for COPD management.

Triple Therapy Offers New Hope for COPD Patients

These findings offer a glimmer of hope for individuals struggling with COPD. The triple therapy approach provides a more effective way to manage the disease, reducing the frequency of exacerbations and improving overall quality of life. It's like providing a camel with a triple-layered blanket to shield it from the harsh desert winds, giving it the strength to journey on.

Navigating the Desert of COPD

While triple therapy presents a powerful tool in the battle against COPD, it is important to note that the side effect profile mirrors the individual components of the combination. As researchers continue to explore the complexities of COPD and the effectiveness of triple therapy, we can hope for even more effective and safer treatments to help individuals navigate the challenging landscape of this chronic lung disease.

Dr.Camel's Conclusion

COPD can feel like a vast and unpredictable desert. This research is like discovering a new oasis—a triple therapy combination that offers a promising avenue for effective COPD management. It's a testament to the ongoing quest for better treatments that can help patients navigate the challenges of chronic lung disease and reclaim their quality of life.

Date :
  1. Date Completed 2019-06-03
  2. Date Revised 2019-06-03
Further Info :

Pubmed ID

30463457

DOI: Digital Object Identifier

10.1080/17476348.2019.1548937

Related Literature

SNS
PICO Info
in preparation
Languages

English

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