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Adverse side effects of dexamethasone in surgical patients.

Author: DeVriesJ Hans, Farhang-RaziViolet, HermanidesJeroen, HollmannMarkus W, KrankePeter, PoldermanJorinde Aw, PreckelBenedikt, Van DierenSusan

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Dexamethasone is widely used in the perioperative period for various purposes, but its long-term effects are well-documented. This study explores whether a single steroid load during surgery has negative effects during the postoperative period.
Paper Details　
Original Abstract of the Article :
In the perioperative period, dexamethasone is widely and effectively used for prophylaxis of postoperative nausea and vomiting (PONV), for pain management, and to facilitate early discharge after ambulatory surgery.Long-term treatment with steroids has many side effects, such as adrenal insufficienc...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426282/

データ提供：米国国立医学図書館（NLM）

Dexamethasone: A Double-Edged Sword in the Perioperative Period

Dexamethasone, a commonly used corticosteroid, has a wide range of applications in the perioperative period. This research delves into the potential adverse side effects of dexamethasone in surgical patients, particularly focusing on the impact of a single steroid load during surgery. It's like a camel caravan navigating a challenging desert terrain, where a seemingly beneficial resource can have unintended consequences.

Navigating the Potential Risks of Dexamethasone

The study highlights the known adverse side effects of long-term steroid use, including adrenal insufficiency, increased infection risk, and metabolic disturbances. However, the potential impact of a single steroid load during surgery remains an area of ongoing research. It's like carefully assessing the potential benefits and risks of a shortcut through a desert region, ensuring a balanced approach to minimize potential hazards.

Understanding the Risks and Benefits of Dexamethasone

This study underscores the importance of considering the potential risks and benefits of dexamethasone use in surgical patients. While it offers numerous benefits, including pain management and reduced postoperative nausea, a careful assessment of potential side effects is crucial for making informed decisions. It's like choosing the right path through the desert, weighing the advantages and disadvantages of different routes to ensure a safe and successful journey.

Dr.Camel's Conclusion

This study provides a valuable reminder of the importance of carefully weighing the risks and benefits of dexamethasone use in surgical patients. By understanding the potential side effects and carefully monitoring patients, healthcare providers can optimize the use of this valuable medication, ensuring a safe and successful journey for their patients. It's like navigating the desert with caution and foresight, ensuring a healthy and fulfilling journey for the caravan.

Date :
  1. Date Completed 2019-03-22
  2. Date Revised 2022-08-30
Further Info :

Pubmed ID

30480776

DOI: Digital Object Identifier

PMC6426282

SNS
PICO Info
in preparation
Languages

English

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