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Prevalence and determinants of anti-tuberculosis treatment non-adherence in Ethiopia: A systematic review and meta-analysis.

Author: DessieGetnet, GebrieAlemu, IslamSheikh Mohammed Shariful, KirossDessalegn, TesfayeBekele, WagnewFasil, ZegeyeAbriham

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This meta-analysis of 13 studies in Ethiopia evaluated the prevalence of non-adherence to tuberculosis treatment. The pooled prevalence was 21.29%. Forgetfulness, fear of side effects, long waiting times at healthcare facilities, and perceived distance to healthcare were identified as significant determinants of non-adherence. The study highlights the need for interventions to address these factors and improve medication adherence.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Tuberculosis is a global public health problem. One of the overarching dilemmas and challenges facing most tuberculosis program is non-adherence to treatment. However, in Ethiopia there are few studies with variable and inconsistent findings regarding non-adherence to treatment for tuber...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328265/

データ提供：米国国立医学図書館（NLM）

Non-Adherence to Anti-Tuberculosis Treatment in Ethiopia: A Meta-Analysis

The fight against [tuberculosis (TB)] is a global health priority, requiring [effective treatment and adherence] to achieve [successful outcomes]. This meta-analysis investigates the [prevalence and determinants] of [non-adherence to anti-tuberculosis treatment] in [Ethiopia]. The study synthesizes data from [13 studies] to understand the [magnitude of the problem] and [identify key factors contributing to non-adherence].

High Prevalence of Non-Adherence to TB Treatment in Ethiopia

The meta-analysis revealed a [high pooled prevalence] of [non-adherence to anti-tuberculosis treatment] in [Ethiopia], with [21.29% of patients] experiencing [non-adherence]. The study identified [several factors] associated with [non-adherence], including [forgetfulness, fear of side effects, long waiting times, and perceived distance to health institutions].

Addressing Non-Adherence to Improve TB Treatment Outcomes

This research highlights the need for [targeted interventions] to address [non-adherence] in [TB treatment] in [Ethiopia]. The study underscores the importance of [patient education, medication adherence support, and addressing barriers] to [ensure successful completion of treatment]. This research calls for [improved access to healthcare] and [patient-centered care approaches] to [improve TB treatment outcomes] and [reduce the spread of the disease].

Dr.Camel's Conclusion

This meta-analysis is a stark reminder of the challenges we face in the fight against [TB] in [Ethiopia]. The high prevalence of [non-adherence] underscores the importance of [proactive strategies] to [address the underlying factors] and [support patients] in [successfully completing their treatment]. This research provides a roadmap for [improving TB control efforts] and [improving the health outcomes] of those affected by this devastating disease.

Date :
  1. Date Completed 2019-10-21
  2. Date Revised 2023-10-05
Further Info :

Pubmed ID

30629684

DOI: Digital Object Identifier

PMC6328265

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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