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Original Abstract of the Article :
D-penicillamine (DPA) leads to side effects in different ways: collagen and elastin crosslinking are inhibited, which results in thin and vulnerable skin, cutis laxa, elastosis perforans serpiginosa, wound healing defects and embryopathy. Toxic influences effect thrombo- and leukocytopenia (incidenc...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3063003
データ提供:米国国立医学図書館(NLM)
D-Penicillamine: Side Effects, Pathogenesis, and Risk Mitigation
The field of drug therapy is like a vast desert, often navigating the challenges of balancing therapeutic benefits with potential side effects. This article explores the side effects, pathogenesis, and risk mitigation strategies associated with D-penicillamine (DPA), a medication used to treat various conditions, including rheumatoid arthritis and Wilson's disease. The authors provide a comprehensive overview of DPA's side effects, including its impact on collagen and elastin crosslinking, its potential to induce autoimmune phenomena, and its risk factors. The article highlights the importance of careful patient selection, regular monitoring, and risk management strategies to minimize the occurrence of adverse events.
D-Penicillamine: Balancing Benefits and Risks
This article emphasizes the need for careful consideration of the potential side effects associated with D-penicillamine therapy. The authors provide valuable insights into the various mechanisms by which DPA can lead to adverse events, highlighting the importance of risk factor assessment and regular monitoring to minimize the occurrence of complications. The article underscores the importance of balancing the therapeutic benefits of DPA with its potential risks, ensuring that patients receive appropriate care and management strategies to minimize the likelihood of adverse outcomes.
Navigating the Desert of Drug Therapy
This article provides a comprehensive overview of the side effects, pathogenesis, and risk mitigation strategies associated with D-penicillamine therapy. The authors highlight the importance of careful patient selection, regular monitoring, and risk management strategies to minimize the occurrence of adverse events. This article serves as a valuable resource for clinicians navigating the desert of drug therapy, providing essential information for making informed decisions regarding D-penicillamine treatment and minimizing the likelihood of adverse outcomes.
Dr.Camel's Conclusion
This article provides a comprehensive overview of the side effects, pathogenesis, and risk mitigation strategies associated with D-penicillamine therapy. The authors highlight the importance of careful patient selection, regular monitoring, and risk management strategies to minimize the occurrence of adverse events. This article serves as a valuable resource for clinicians navigating the desert of drug therapy, providing essential information for making informed decisions regarding D-penicillamine treatment and minimizing the likelihood of adverse outcomes.
Date :
- Date Completed 1989-02-23
- Date Revised 2013-11-21
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