Assessment of Efficacy and Tolerability of Medicinal Cannabinoids in Patients With Multiple Sclerosis: A Systematic Review and Meta-analysis.

Author: FarréMagí, PapaseitEsther, TorrensMarta, Torres-MorenoMari Carmen

Paper Details 
Original Abstract of the Article :
IMPORTANCE: Cannabinoids have antispastic and analgesic effects; however, their role in the treatment of multiple sclerosis (MS) symptoms is not well defined. OBJECTIVE: To conduct a systematic review and meta-analysis to assess the efficacy and tolerability of medicinal cannabinoids compared with ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324456/

データ提供:米国国立医学図書館(NLM)

Cannabis for Multiple Sclerosis: Navigating the Sands of Relief

My research often takes me to the intersection of [neurology] and [alternative medicine], where I explore the potential benefits and risks of [medicinal cannabis]. This study examines the use of [cannabinoids] for the treatment of [multiple sclerosis (MS)] symptoms, specifically focusing on [spasticity, pain, and bladder dysfunction]. Researchers conducted a comprehensive [systematic review and meta-analysis] of available clinical trials to assess the efficacy and safety of cannabinoids in patients with MS.

A Mixed Bag of Results: The Efficacy and Tolerability of Cannabinoids

The meta-analysis found [limited evidence for the efficacy of cannabinoids] in treating MS symptoms, with [small effect sizes] observed for spasticity, pain, and bladder dysfunction. However, the study also revealed [a higher risk of adverse events and withdrawals due to adverse events] associated with cannabinoid use. These findings highlight the need for careful consideration of the potential benefits and risks of cannabinoids in the treatment of MS.

Balancing the Scales: Finding the Right Path for MS Patients

Imagine a camel traversing a desert with a variety of obstacles, such as sand dunes, rocky terrain, and scorching temperatures. Some camels may be more resilient and able to navigate these obstacles with relative ease, while others may struggle. Similarly, patients with MS experience a wide range of symptoms and require individualized treatment approaches. This research helps us understand the potential benefits and risks of cannabinoids for MS patients, allowing us to find the best path for each individual, just as a camel navigator would carefully choose the most suitable route through the desert.

Dr.Camel's Conclusion

This research offers a comprehensive assessment of the use of cannabinoids in MS treatment. The findings suggest that while cannabinoids may offer some benefits for certain MS symptoms, the potential for adverse events requires careful consideration. Just as a wise camel navigator chooses the safest path through the desert, healthcare providers must carefully weigh the potential benefits and risks of cannabinoids in treating MS.

Date :
  1. Date Completed 2019-09-30
  2. Date Revised 2020-03-09
Further Info :

Pubmed ID

30646241

DOI: Digital Object Identifier

PMC6324456

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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