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Epistaxis Risk Associated with Intranasal Corticosteroid Sprays: A Systematic Review and Meta-analysis.

Author: AlexanderBailin H, BabcockCasey M, HarrisWilliam C, McCoulEdward D, RileyCharles A, WuEric L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Intranasal corticosteroids (INCSs) increase the risk of epistaxis compared to placebo, with beclomethasone hydrofluoroalkane, fluticasone furoate, mometasone furoate, and fluticasone propionate associated with the highest risk.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Intranasal corticosteroids (INCSs) are widely utilized for the treatment of allergic rhinitis. Epistaxis is a known adverse effect of INCSs, but it is not known if the risk of epistaxis differs among INCSs. DATA SOURCES: Systematic review of primary studies identified through Medline, Em...See full text at original site
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引用元：
https://doi.org/10.1177/0194599819832277

データ提供：米国国立医学図書館（NLM）

Intranasal Corticosteroids: A Balancing Act for Allergy Relief

This study delves into the world of intranasal corticosteroids (INCSs), a common treatment for allergic rhinitis. It's like a desert expedition, where researchers are exploring the terrain of allergy management. The study reviews the use of INCSs and their potential for causing epistaxis, commonly known as nosebleeds. The researchers conducted a meta-analysis of clinical trials to assess the risk of epistaxis associated with various INCS agents. The analysis revealed an overall increased risk of epistaxis with INCS use compared to placebo. They also found that certain INCS agents were associated with a higher risk of epistaxis than others.

Intranasal Corticosteroids and Epistaxis: A Risk-Benefit Analysis

This research highlights the need for a careful assessment of the risks and benefits of intranasal corticosteroids (INCSs) for allergy relief. It's like navigating a desert with hidden dangers - while INCSs can effectively manage allergy symptoms, they also carry a potential risk of nosebleeds. The study's findings emphasize the importance of choosing the right INCS agent based on individual needs and risk factors.

Navigating the Desert of Allergy Management

This study encourages us to be mindful of the potential side effects of intranasal corticosteroids (INCSs) when managing allergies. It's like a desert journey, where we need to be aware of the terrain and potential hazards along the way. Patients should discuss their allergy symptoms and concerns with their doctor to determine the most appropriate treatment options and to minimize the risk of side effects.

Dr.Camel's Conclusion

Intranasal corticosteroids offer a valuable tool for managing allergies, but like a desert oasis, they require careful navigation. This study reminds us to be aware of the potential risks and benefits of INCS use and to make informed decisions based on a thorough understanding of the available options. It's a journey of discovery, where we strive to find the best possible solutions for allergy management, ensuring a comfortable and healthy journey through the desert of allergy symptoms.

Date :
  1. Date Completed 2020-01-27
  2. Date Revised 2020-01-27
Further Info :

Pubmed ID

30779679

DOI: Digital Object Identifier

10.1177/0194599819832277

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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