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Trigeminal neuralgia secondary to multiple sclerosis: from the clinical picture to the treatment options.

Author: Di StefanoGiulia, MaarbjergStine, TruiniAndrea

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Trigeminal neuralgia is a painful condition that can be caused by multiple sclerosis. While sodium-channel blockers like carbamazepine and oxcarbazepine are the first-line treatment, their side effects often lead to the need for neurosurgery. More research is needed to develop better treatments for this condition.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Trigeminal neuralgia is one of the most characteristic and difficult to treat neuropathic pain conditions in patients with multiple sclerosis. The present narrative review addresses the current evidence on diagnostic tests and treatment of trigeminal neuralgia secondary to multiple scler...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734488/

データ提供：米国国立医学図書館（NLM）

Trigeminal Neuralgia in Multiple Sclerosis: A Comprehensive Review

Navigating the complex world of neurological disorders requires an understanding of the intricate interplay between different systems. This review delves into the challenges of managing trigeminal neuralgia, a debilitating pain condition, in patients with multiple sclerosis (MS).

The authors present a comprehensive overview of trigeminal neuralgia in MS, focusing on diagnostic approaches and treatment options. They highlight the need for dedicated MRI scans to identify pontine demyelinating plaques, which are key to understanding the underlying causes. They also explore the potential role of neurovascular compression, adding another layer of complexity to the diagnosis. The review emphasizes the current reliance on sodium-channel blockers, like carbamazepine and oxcarbazepine, as first-line therapy, while acknowledging the significant side effects. Surgical interventions, including microvascular decompression and gamma knife radiosurgery, are discussed as alternative treatment options.

A Multifaceted Approach to Trigeminal Neuralgia in MS

This review underscores the need for a multifaceted approach to managing trigeminal neuralgia in MS, taking into consideration both diagnostic and therapeutic challenges.

A Camel's Perspective on Neurological Disorders

The desert is a harsh environment, and just as a camel adapts to survive its surroundings, so too must we adapt our approach to treating neurological disorders. This review highlights the importance of understanding the intricate connections between different neurological systems and the need for tailored treatment strategies.

Dr.Camel's Conclusion

Trigeminal neuralgia in MS presents a complex and challenging clinical scenario. This review provides a comprehensive overview of the current understanding of the disorder, highlighting the need for improved diagnostic tools and more effective treatment options.

Date :
  1. Date Completed 2019-04-16
  2. Date Revised 2023-10-13
Further Info :

Pubmed ID

30782116

DOI: Digital Object Identifier

PMC6734488

Related Literature

Article Analysis
・Side Effects of oxcarbazepine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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