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Controlled trial of bowel rest in the treatment of severe acute colitis.

Author: ColinR, GalmicheJ P, HecketsweilerP, Lennard-JonesJ E, LereboursE, McIntyreP B, Powell-TuckJ, WoodS R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 47 patients with severe, acute, non-infective colitis found that bowel rest did not improve outcomes for patients treated with intravenous prednisolone.
Paper Details　
Original Abstract of the Article :
In a prospective, randomised clinical trial, 47 patients with severe, acute, non-infective colitis treated with 60 mg intravenous prednisolone daily, received either bowel rest with parenteral nutrition or oral diet. Although those who received 'bowel rest' experienced a reduction in daily stool wei...See full text at original site
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引用元：
https://doi.org/10.1136/gut.27.5.481

データ提供：米国国立医学図書館（NLM）

Bowel Rest: A Debated Strategy for Colitis

This study delves into the complexities of colitis treatment, investigating the effectiveness of bowel rest in patients with severe, acute colitis. It's like a desert traveler trying to find the best way to rest and recover after a long journey. The researchers designed a clinical trial to compare the outcomes of two treatment approaches: bowel rest with parenteral nutrition and an oral diet. The goal was to determine which approach provided better results in terms of recovery and reducing the need for surgery.

The study found that while bowel rest did reduce stool weight, it did not significantly impact the need for surgery or the overall mortality rate. It's like discovering that a specific type of desert plant may not be the most effective for providing shade. However, the research did reveal that ulcerative colitis and Crohn's disease, two types of colitis, responded differently to the treatments.

Understanding the Individual Nature of Colitis

This study highlights the importance of understanding the individual nature of colitis. It's like discovering that different types of sand dunes react differently to the same wind. The research suggests that different treatment approaches might be needed for different types of colitis.

Making Informed Treatment Decisions

This study is crucial for making informed treatment decisions for patients with colitis. It's like navigating a desert with a map, understanding the different paths and choosing the best route for recovery. The research provides evidence to support the use of intravenous prednisolone as a primary treatment for severe colitis, while also suggesting that bowel rest might not always be necessary.

Dr. Camel's Conclusion

This study sheds light on the intricacies of colitis treatment. It's a reminder that there's no one-size-fits-all approach to managing this condition. It's like understanding the unique characteristics of different desert ecosystems.

Date :
  1. Date Completed 1986-06-16
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

3084344

DOI: Digital Object Identifier

10.1136/gut.27.5.481

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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