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Evaluation of the Effects of Clobazam on Seizure Control and Quality of Life in Children With Lennox-Gastaut Syndrome: A Pilot Study.

Author: AgarwalNitin, CheemaZaheer, FarooqOsman, HamiltonDeanna, ParrishJoy, WeinstockArie

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Clobazam, used as adjunctive therapy for children with Lennox-Gastaut syndrome, showed improvement in seizure frequency and parent-reported behavior and quality of life. Significant improvement was seen in cognition, social activities, behavior, and overall quality of life.
Paper Details　
Original Abstract of the Article :
PURPOSE: This is a prospective study of children with Lennox-Gastaut syndrome receiving clobazam as adjunctive therapy. This pilot study aims to examine medication effectiveness as it relates to seizure reduction, as well as improvement in parent-reported behavior and quality of life (QOL). METHODS...See full text at original site
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引用元：
https://doi.org/10.1177/0883073819836534

データ提供：米国国立医学図書館（NLM）

Clobazam: A Beacon of Hope for Lennox-Gastaut Syndrome

Lennox-Gastaut syndrome (LGS), a severe form of epilepsy, presents a significant challenge for both patients and healthcare professionals. This study investigates the potential of clobazam, an anticonvulsant medication, as adjunctive therapy for children with LGS. The researchers explored the effects of clobazam on seizure control, behavior, and quality of life (QOL) in a group of children with LGS.

Positive Impact on QOL: Clobazam's Role in Lennox-Gastaut Syndrome

The study found significant improvement in the QOL of children with LGS receiving clobazam as adjunctive therapy. The medication was effective in reducing seizure frequency, improving cognition, social activities, behavior, and overall QOL. These positive findings offer hope for children with LGS and their families.

A Ray of Hope: Dr. Camel's Reflections

This research provides a glimmer of hope for children with Lennox-Gastaut syndrome, highlighting the potential of clobazam in improving their quality of life. Like a camel finding an oasis in the desert, these findings offer a much-needed source of comfort and hope.

Dr. Camel's Conclusion

This pilot study provides promising evidence for the efficacy of clobazam as adjunctive therapy for Lennox-Gastaut syndrome. The medication demonstrated positive effects on seizure control, behavior, and quality of life, offering hope for children with this challenging condition.

Date :
  1. Date Completed 2020-06-22
  2. Date Revised 2020-06-22
Further Info :

Pubmed ID

30913948

DOI: Digital Object Identifier

10.1177/0883073819836534

Related Literature

Article Analysis
・Effects of clobazam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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